Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6739162 | 0.98 | CHRNB2 (0.44) | CHRNB2CHRNA7CHRNA4S1PR1S1PR3 | |
| SCHEMBL9488981 | 0.88 | CYP1A2 (0.38) | CHRNB2CHRNA7CHRNA4ALDH1A1CYP1A2 | |
| SCHEMBL28869330 | 0.87 | CYP1A2 (0.40) | CHRNB2CHRNA7CHRNA4ALDH1A1CYP1A2 | |
| SCHEMBL11070667 | 0.82 | ALDH1A1 (0.33) | CHRNB2CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL9692949 | 0.81 | NOS3 (0.43) | CHRNB2CHRNA7CHRNA4ALDH1A1 | |
| SCHEMBL28358596 | 0.81 | CHRNB2 (0.46) | CHRNB2CHRNA7CHRNA4S1PR1S1PR3 | |
| SCHEMBL28355004 | 0.79 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA4S1PR1S1PR3 | |
| SCHEMBL15958842 | 0.79 | CHRNB2 (0.44) | CHRNB2CHRNA7CHRNA4S1PR1S1PR3 | |
| SCHEMBL28542197 | 0.79 | CHRNB2 (0.44) | CHRNB2CHRNA7CHRNA4S1PR1S1PR3 | |
| SCHEMBL28358578 | 0.78 | CHRNB2 (0.43) | CHRNB2CHRNA7CHRNA4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011053801-A2 | METHODS AND COSMETIC PREPARATIONS FOR THE SUSTAINED DELIVERY OF THERAPEUTIC AGENTS TO THE EYE | INTRATUS, INC. (US) | 2011-05-05 | — | — | WO | disclosed |
| WO-2011053792-A2 | METHODS AND COMPOSITIONS FOR SUSTAINED DELIVERY OF DRUGS | INTRATUS, INC. (US) | 2011-05-05 | — | — | WO | disclosed |