SCHEMBL6739162

SCHEMBL6739162

CCCCCCC1CCCCN(N)C1=O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.44
CHRNA7 P36544 1/20 0.44
CHRNA4 P43681 1/20 0.44
S1PR1 P21453 3/20 0.38
S1PR3 Q99500 3/20 0.38
S1PR5 Q9H228 3/20 0.38
CYP1A2 P05177 3/20 0.37
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 3/20 0.35
NAAA Q02083 1/20 0.33
GRM2 Q14416 1/20 0.33
S1PR2 O95136 1/20 0.33
S1PR4 O95977 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1907356 0.98 CHRNB2 (0.42) CHRNB2CHRNA7CHRNA4S1PR1S1PR3
SCHEMBL28869330 0.89 CYP1A2 (0.40) CHRNB2CHRNA7CHRNA4CYP1A2HTT
SCHEMBL9488981 0.87 CYP1A2 (0.38) CHRNB2CHRNA7CHRNA4CYP1A2HTT
SCHEMBL11070667 0.84 ALDH1A1 (0.33) CHRNB2CHRNA7CHRNA4ALDH1A1
SCHEMBL28358596 0.83 CHRNB2 (0.46) CHRNB2CHRNA7CHRNA4S1PR1S1PR3
SCHEMBL28542197 0.81 CHRNB2 (0.44) CHRNB2CHRNA7CHRNA4S1PR1S1PR3
SCHEMBL15958842 0.81 CHRNB2 (0.44) CHRNB2CHRNA7CHRNA4S1PR1S1PR3
SCHEMBL28358773 0.80 CHRNB2 (0.43) CHRNB2CHRNA7CHRNA4S1PR1S1PR3
SCHEMBL28358578 0.80 CHRNB2 (0.43) CHRNB2CHRNA7CHRNA4S1PR1S1PR3
SCHEMBL9692949 0.80 NOS3 (0.43) CHRNB2CHRNA7CHRNA4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6683179-B2 Preparation of caprolactam BASF AKTIENGESELLSCHAFT (DE) 2004-01-27 US disclosed
US-20030105322-A1 Method for producing caprolactam on the basis of 6-aminocapronitrile and subsequent purification by crystallization WURTZEL, ALAN 2003-06-05 US disclosed
EP-1280767-A1 METHOD FOR PRODUCING CAPROLACTAM ON THE BASIS OF 6-AMINOCAPRONITRILE AND SUBSEQUENT PURIFICATION BY CRYSTALLIZATION BASF AKTIENGESELLSCHAFT (DE) 2003-02-05 EP disclosed
WO-2001083443-A1 METHOD FOR PRODUCING CAPROLACTAM ON THE BASIS OF 6-AMINOCAPRONITRILE AND SUBSEQUENT PURIFICATION BY CRYSTALLIZATION BASF AKTIENGESELLSCHAFT (DE) 2001-11-08 WO disclosed