Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MASP2 | O00187 | 3/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906797 | 0.83 | OPRD1 (0.47) | TACR1CTSSCTSKMASP2OPRD1 | |
| SCHEMBL1906788 | 0.83 | KLKB1 (0.49) | CTSSCTSKHRH4NAMPT | |
| SCHEMBL1906790 | 0.83 | KLKB1 (0.49) | CTSSCTSKHRH4NAMPT | |
| SCHEMBL1906792 | 0.83 | OPRD1 (0.47) | TACR1CTSSCTSKMASP2OPRD1 | |
| SCHEMBL1433336 | 0.82 | TACR1 (0.46) | TACR1CTSSCTSKMASP2FNTA | |
| SCHEMBL1903462 | 0.81 | NAMPT (0.50) | CYP3A4CTSSCTSKMASP2HRH4 | |
| SCHEMBL1904790 | 0.81 | OPRD1 (0.48) | CTSSCTSKMASP2OPRD1PSMB5 | |
| SCHEMBL1902802 | 0.81 | OPRD1 (0.46) | CTSSCTSKMASP2OPRD1HRH4 | |
| SCHEMBL1902805 | 0.81 | OPRD1 (0.46) | CTSSCTSKMASP2OPRD1HRH4 | |
| SCHEMBL3154370 | 0.81 | MASP2 (0.47) | CYP3A4CTSSCTSKMASP2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |