SCHEMBL190799

SCHEMBL190799

Nc1ccc(CS(=O)(=O)O)c(N)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.46
ALDH1A1 P00352 5/20 0.46
RECQL P46063 3/20 0.46
HSD17B10 Q99714 2/20 0.46
CASP1 P29466 2/20 0.46
THRB P10828 2/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
TDP1 Q9NUW8 4/20 0.42
NT5E P21589 2/20 0.39
LMNA P02545 1/20 0.36
CYP2D6 P10635 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
NSD2 O96028 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114264 0.84 ALDH1A1 (0.50) TSHRALDH1A1RECQLHSD17B10CASP1
SCHEMBL10883664 0.81 TSHR (0.43) TSHRALDH1A1RECQLHSD17B10CASP1
SCHEMBL27619224 0.81 ADRA2B (0.41) TSHRALDH1A1RECQLHSD17B10CASP1
SCHEMBL8968519 0.81 KEAP1 (0.39) TSHRALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL29084339 0.80 TSHR (0.38) TSHRALDH1A1RECQLHSD17B10CASP1
SCHEMBL8968024 0.79 KEAP1 (0.38) TSHRALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL7793142 0.79 CTDSP1 (0.40) TSHRALDH1A1RECQLHSD17B10CASP1
SCHEMBL11502375 0.77 TSHR (0.52) TSHRALDH1A1RECQLHSD17B10CASP1
SCHEMBL21412655 0.77 GAA (0.61) TSHRALDH1A1HSD17B10TDP1MAPT
SCHEMBL10887389 0.77 ALDH1A1 (0.40) TSHRALDH1A1RECQLHSD17B10CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553714-B1 Highly crosslinked, low VOC surface coating compositions comprising polyurethane dispersions SHERWIN WILLIAMS CO (US) 1995-12-27 EP claimed
EP-0553714-A1 Highly crosslinked, low VOC surface coating compositions comprising polyurethane dispersions THE SHERWIN-WILLIAMS COMPANY (US) 1993-08-04 EP claimed
CN-112004853-B Aqueous composition containing uretdione groups and process for preparing the same 科思创知识产权两合公司 2023-07-28 CN disclosed
CN-112041367-B Aqueous composition containing uretdione groups and process for preparing the same 科思创知识产权两合公司 2023-05-16 CN disclosed
US-20210024680-A1 AQUEOUS URETDIONE GROUP-CONTAINING COMPOSITIONS AND METHOD FOR PRODUCING SAME COVESTRO DEUTSCHLAND AG (DE) 2021-01-28 US disclosed
US-20210024679-A1 CATALYST SYSTEM FOR URETDIONE DISPERSIONS COVESTRO DEUTSCHLAND AG (DE) 2021-01-28 US disclosed
EP-3768750-A1 AQUEOUS URETDIONE GROUP-CONTAINING COMPOSITIONS AND METHOD FOR PRODUCING SAME Covestro Intellectual Property GmbH & Co. KG (DE) 2021-01-27 EP disclosed
EP-3768751-A1 AQUEOUS URETDIONE GROUP-CONTAINING COMPOSITIONS AND METHOD FOR PRODUCING SAME Covestro Intellectual Property GmbH & Co. KG (DE) 2021-01-27 EP disclosed
EP-3768749-A1 AQUEOUS URETDIONE GROUP-CONTAINING COMPOSITIONS AND METHOD FOR PRODUCING SAME Covestro Deutschland AG (DE) 2021-01-27 EP disclosed
EP-3768748-A1 CATALYST SYSTEM FOR URETDIONE DISPERSIONS Covestro Deutschland AG (DE) 2021-01-27 EP disclosed
US-20210017323-A1 AQUEOUS URETDIONE GROUP-CONTAINING COMPOSITIONS AND METHOD FOR PRODUCING SAME COVESTRO LLC 2021-01-21 US disclosed
EP-0407968-A2 Semi-continuous process for the preparation of polyurethaneurea aqueous dispersions THE DOW CHEMICAL COMPANY (US) 1991-01-16 EP disclosed
WO-1990006187-A1 PROCESS FOR THE PRODUCTION OF A MULTI-LAYER PAINT COATING, WATER-DILUTABLE PAINT, PROCESS FOR THE PRODUCTION OF CROSS-LINKED POLYMER MICROPARTICLES AND CROSS-LINKED MICROPARTICLES BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) 1990-06-14 WO disclosed
WO-1990006186-A1 PROCESS FOR THE PRODUCTION OF A MULTI-LAYER COATING, WATER-DILUTABLE COATING COMPOSITIONS, WATER-DILUTABLE EMULSION POLYMERS AND PROCESS FOR THE PRODUCTION OF WATER-DILUTABLE EMULSION POLYMERS BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) 1990-06-14 WO disclosed
US-4880867-A Aqueous coating compositions, a process for their preparation and method of using the same 501 HERBERTS GESELLSCHAFT MIT BESCHRANKTER (DE) 1989-11-14 US disclosed
US-4851460-A Aqueous coating composition, process for its preparation and its use HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-07-25 US disclosed
EP-0260447-A2 Aqueous coating composition, process for its preparation and its use Herberts Gesellschaft mit beschränkter Haftung (DE) 1988-03-23 EP disclosed
EP-0256540-A2 Aqueous coating, process for its preparation and its use Herberts Gesellschaft mit beschränkter Haftung (DE) 1988-02-24 EP disclosed
EP-0128272-B1 2,4-DIAMINOBENZENE DERIVATES, THEIR PRODUCTION AND USE AS COUPLING SUBSTANCES Henkel Kommanditgesellschaft auf Aktien (DE) 1986-10-15 EP disclosed
EP-0128272-A1 2,4-Diaminobenzene derivates, their production and use as coupling substances Henkel Kommanditgesellschaft auf Aktien (DE) 1984-12-19 EP disclosed