Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.62 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.62 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 4/20 | 0.58 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607881 | 0.87 | KIF11 (0.61) | GRIA1CACNG8PDE3BPDE3ADAPK3 | |
| SCHEMBL1900635 | 0.86 | PDE3B (0.64) | GRIA1CACNG8PDE3BPDE3APGR | |
| SCHEMBL1897593 | 0.82 | PDE3B (0.68) | GRIA1CACNG8PDE3BPDE3APGR | |
| SCHEMBL1896888 | 0.82 | TDP2 (0.70) | GRIA1CACNG8PDE3BPDE3APGR | |
| SCHEMBL18189476 | 0.80 | GRIA1 (0.82) | GRIA1CACNG8PDE3BPDE3APGR | |
| SCHEMBL27859220 | 0.80 | PDE3B (0.64) | GRIA1CACNG8PDE3BPDE3APGR | |
| SCHEMBL1899619 | 0.79 | PDE3B (0.56) | GRIA1CACNG8PDE3BPDE3APGR | |
| SCHEMBL1900155 | 0.79 | AHR (0.77) | GRIA1CACNG8PDE3BPDE3APGR | |
| SCHEMBL18189405 | 0.78 | GRIA1 (0.70) | GRIA1CACNG8PDE3BPDE3APGR | |
| SCHEMBL3132725 | 0.77 | PGR (0.73) | GRIA1CACNG8PDE3BPDE3APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056985-A2 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2011-05-12 | — | — | WO | disclosed |