SCHEMBL19081989

SCHEMBL19081989

c1cc(-c2c3ccccc3c(-c3ccc4ccccc4c3)c3ccccc23)cc(-c2cc3c4ccccc4sc3c3c2oc2cc4ccccc4cc23)c1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
S1PR5 Q9H228 13/20 0.37
S1PR4 O95977 10/20 0.37
ALOX5 P09917 1/20 0.35
PRKDC P78527 2/20 0.34
GPR84 Q9NQS5 1/20 0.33
ESR2 Q92731 2/20 0.33
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
ESR1 P03372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19081948 0.91 ALOX5 (0.34) S1PR5S1PR4ALOX5PRKDCESR2
SCHEMBL17944810 0.86 S1PR5 (0.34) S1PR5S1PR4ALOX5GPR84ESR2
SCHEMBL19082008 0.84 TNKS (0.34) ALOX5ESR2TNKSTNKS2ESR1
SCHEMBL19076741 0.84 ALOX5 (0.37) S1PR5S1PR4ALOX5PRKDCGPR84
SCHEMBL19081864 0.83 TNKS (0.35) ALOX5PRKDCESR2TNKSTNKS2
SCHEMBL19080001 0.82 GPR84 (0.43) ALOX5PRKDCGPR84ESR2ESR1
SCHEMBL17944631 0.82 ALOX5 (0.40) S1PR5S1PR4ALOX5GPR84TNKS
SCHEMBL24343176 0.82 ALOX5 (0.36) S1PR5S1PR4ALOX5PRKDCGPR84
SCHEMBL19081597 0.82 ALOX5 (0.38) ALOX5PRKDCGPR84ESR2ESR1
SCHEMBL19082306 0.82 ALOX5 (0.38) S1PR5S1PR4ALOX5GPR84TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-04 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same CRY1, CRY2, CCNT1 S1PR5 4728/4885S1PR4 4594/4885ALOX5 1939/4885
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 S1PR5 4728/4885S1PR4 4594/4885ALOX5 1939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.