SCHEMBL19081864

SCHEMBL19081864

c1ccc(-c2ccc(-c3c4ccccc4c(-c4cc5c6ccccc6sc5c5c4oc4cc6ccccc6cc45)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TNKS O95271 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
ESR2 Q92731 2/20 0.35
ESR1 P03372 1/20 0.34
MAPT P10636 2/20 0.32
PTPN1 P18031 1/20 0.31
F9 P00740 1/20 0.30
ALOX5 P09917 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
MPI P34949 1/20 0.30
KMT2A Q03164 1/20 0.30
SLC9A1 P19634 1/20 0.30
PRKDC P78527 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19082008 0.92 TNKS (0.34) TNKSTNKS2ESR2ESR1MAPT
SCHEMBL19081948 0.86 ALOX5 (0.34) TNKSTNKS2ESR2ESR1MAPT
SCHEMBL19081868 0.83 PTPN1 (0.33) TNKSTNKS2ESR2ESR1MAPT
SCHEMBL19081989 0.83 S1PR5 (0.37) TNKSTNKS2ESR2ESR1ALOX5
SCHEMBL19082186 0.81 TNKS (0.38) TNKSTNKS2ESR2ESR1MAPT
SCHEMBL24004520 0.81 TNKS (0.39) TNKSTNKS2ESR2ESR1MAPT
SCHEMBL17589552 0.81 GPR84 (0.39) ESR2ESR1MAPTALOX5KDM4E
SCHEMBL19081774 0.80 ABCG2 (0.40) TNKSTNKS2ESR2ESR1MAPT
SCHEMBL19081784 0.79 ESR2 (0.38) TNKSTNKS2ESR2ESR1MAPT
SCHEMBL19081777 0.78 ESR2 (0.36) ESR2ESR1PTPN1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-04 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same CRY1, CRY2, CCNT1 TNKS 2635/4885TNKS2 2644/4885ESR2 542/4885
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 TNKS 2635/4885TNKS2 2644/4885ESR2 542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.