SCHEMBL19082170

SCHEMBL19082170

c1cc(-c2ccc3ccccc3c2)cc(-c2c3ccccc3c(-c3cc4sc5ccccc5c4c4c3sc3cc5ccccc5cc34)c3ccccc23)c1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
S1PR5 Q9H228 7/20 0.32
S1PR4 O95977 6/20 0.32
PTPN1 P18031 2/20 0.32
ALOX5 P09917 1/20 0.32
CHEK1 O14757 1/20 0.30
WEE1 P30291 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17945678 0.91 PTPN1 (0.37) S1PR5S1PR4PTPN1ALOX5
SCHEMBL17945720 0.90 ALOX5 (0.38) HSD17B1HSD17B2S1PR5S1PR4PTPN1
SCHEMBL19082096 0.89 ESR1 (0.38) PTPN1ALOX5CHEK1WEE1
SCHEMBL17945507 0.89 PTPN1 (0.36) S1PR5S1PR4PTPN1ALOX5CHEK1
SCHEMBL19082166 0.88 ALOX5 (0.35) HSD17B1HSD17B2S1PR5S1PR4PTPN1
SCHEMBL24614940 0.88 HSD17B1 (0.33) HSD17B1HSD17B2S1PR5S1PR4PTPN1
SCHEMBL19082234 0.88 ESR1 (0.35) PTPN1ALOX5CHEK1WEE1
SCHEMBL17945215 0.86 HSD17B1 (0.35) HSD17B1HSD17B2S1PR5S1PR4PTPN1
SCHEMBL19082204 0.86 LIMK1 (0.33) S1PR5S1PR4PTPN1ALOX5CHEK1
SCHEMBL19091020 0.85 CYP1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-04 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same CRY1, CRY2, CCNT1 HSD17B1 1146/4885HSD17B2 1158/4885S1PR5 4728/4885
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 HSD17B1 1146/4885HSD17B2 1158/4885S1PR5 4728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.