Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24614700 | 0.95 | PTPN1 (0.35) | S1PR5S1PR4PTPN1ALOX5GPR84 | |
| SCHEMBL24614709 | 0.92 | PTPN1 (0.34) | PTPN1ALOX5NQO1NQO2MEN1 | |
| SCHEMBL24614682 | 0.91 | S1PR5 (0.36) | HSD17B1HSD17B2S1PR5S1PR4PTPN1 | |
| SCHEMBL24614938 | 0.89 | ALOX5 (0.35) | S1PR5S1PR4PTPN1ALOX5NQO1 | |
| SCHEMBL19082170 | 0.88 | HSD17B1 (0.33) | HSD17B1HSD17B2S1PR5S1PR4PTPN1 | |
| SCHEMBL24614763 | 0.87 | NQO2 (0.35) | PTPN1ALOX5NQO1NQO2MEN1 | |
| SCHEMBL24614686 | 0.87 | GPR84 (0.36) | S1PR5S1PR4PTPN1ALOX5GPR84 | |
| SCHEMBL24614722 | 0.87 | PTPN1 (0.36) | PTPN1ALOX5NQO1NQO2MEN1 | |
| SCHEMBL24614701 | 0.87 | PTPN1 (0.37) | PTPN1ALOX5NQO1NQO2MEN1 | |
| SCHEMBL17945678 | 0.87 | PTPN1 (0.37) | S1PR5S1PR4PTPN1ALOX5GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TMEM109, PIEZO1, L1CAM | HSD17B1 1031/4885HSD17B2 1605/4885S1PR5 4028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.