SCHEMBL19082468

SCHEMBL19082468

COc1cccc(-c2c(F)ccc3ccccc23)c1OC

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
ALDH1A1 P00352 2/20 0.54
RAB9A P51151 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
RPS6KA2 Q15349 3/20 0.41
POLB P06746 1/20 0.41
HTT P42858 1/20 0.41
ABCG2 Q9UNQ0 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
BCHE P06276 2/20 0.40
ACHE P22303 2/20 0.40
STK10 O94804 1/20 0.39
SLK Q9H2G2 1/20 0.39
NISCH Q9Y2I1 1/20 0.39
AHR P35869 1/20 0.39
HPGD P15428 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16673948 0.79 SMN1; SMN2 (0.48) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL23581961 0.78 MAPT (0.73) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL29467232 0.78 MAPT (0.73) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL7719797 0.77 DNMT1 (0.46) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL19082467 0.76 MAPT (0.41) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL19091029 0.75 MAPT (0.54) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL19082494 0.75 MAPT (0.50) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL9950862 0.75 MAPT (0.68) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL19091609 0.74 MAPT (0.39) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL9105836 0.74 NFE2L2 (0.46) MAPTALDH1A1SMN1; SMN2RPS6KA2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-04 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same CRY1, CRY2, CCNT1 MAPT 1294/4885MEN1 277/4885KMT2A 1773/4885
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 MAPT 1294/4885MEN1 277/4885KMT2A 1773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.