SCHEMBL19082494

SCHEMBL19082494

COc1cc(C)ccc1-c1c(F)ccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
KMT2A Q03164 8/20 0.46
MEN1 O00255 6/20 0.46
RAB9A P51151 2/20 0.46
ALDH1A1 P00352 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ACHE P22303 2/20 0.40
ABCG2 Q9UNQ0 3/20 0.39
ABCC1 P33527 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
GAA P10253 2/20 0.39
NPC1 O15118 1/20 0.39
NOX1 Q9Y5S8 1/20 0.39
NISCH Q9Y2I1 1/20 0.38
NQO1 P15559 1/20 0.38
MAOA P21397 1/20 0.38
CYP2A6 P11509 2/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
BCHE P06276 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19091029 0.86 MAPT (0.54) MAPTKMT2AMEN1RAB9AALDH1A1
SCHEMBL19082498 0.78 MEN1 (0.40) MAPTKMT2AMEN1RAB9ATDP1
SCHEMBL19082493 0.76 MAPT (0.42) MAPTKMT2AMEN1RAB9AALDH1A1
SCHEMBL19082468 0.75 MAPT (0.54) MAPTKMT2AMEN1RAB9AALDH1A1
SCHEMBL19091030 0.75 MAPT (0.44) MAPTKMT2AMEN1RAB9AALDH1A1
SCHEMBL19082492 0.75 MAPT (0.41) MAPTKMT2AMEN1RAB9AALDH1A1
SCHEMBL19802987 0.74 L3MBTL1 (0.43) MAPTRAB9AALDH1A1SMN1; SMN2ACHE
SCHEMBL19077651 0.73 ACHE (0.48) MAPTRAB9AALDH1A1SMN1; SMN2ACHE
SCHEMBL34467644 0.73 MAPT (0.57) MAPTKMT2AMEN1RAB9AALDH1A1
SCHEMBL22658238 0.73 MAPT (0.66) MAPTKMT2AMEN1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 MAPT 1294/4885KMT2A 1773/4885MEN1 277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.