SCHEMBL19082510

SCHEMBL19082510

CCOC(=O)c1ccc(Br)cc1-c1ccc2c(c1)sc1ccc3ccccc3c12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.40
ALDH1A1 P00352 4/20 0.40
CDC25B P30305 2/20 0.40
GAA P10253 2/20 0.40
CNR2 P34972 1/20 0.40
GLA P06280 1/20 0.40
KMT2A Q03164 5/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
MEN1 O00255 3/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
TDP1 Q9NUW8 3/20 0.39
MAPT P10636 4/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
CASP3 P42574 1/20 0.38
ATM Q13315 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
CDC25A P30304 1/20 0.38
CDC25C P30307 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17852149 0.80 SLC6A2 (0.52) KDM4EALDH1A1CDC25BGAAGLA
SCHEMBL19082480 0.78 ALDH1A1 (0.47) KDM4EALDH1A1CDC25BGAAGLA
SCHEMBL19082503 0.76 KCNJ11 (0.31) MCL1
SCHEMBL17836985 0.76 CDC25B (0.54) KDM4EALDH1A1CDC25BGAACNR2
SCHEMBL18803777 0.74 CYP1A1 (0.39) ALDH1A1RAB9ASMN1; SMN2MAPTL3MBTL1
SCHEMBL17275796 0.73 CYP2A6 (0.42) ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2
SCHEMBL17852148 0.73 ALDH1A1 (0.49) KDM4EALDH1A1CDC25BGAAGLA
SCHEMBL17382909 0.73 CYP2A6 (0.39) ALDH1A1KMT2AMEN1TDP1MAPT
SCHEMBL13776780 0.72 SLC6A3 (0.57) ALDH1A1CDC25BKMT2ANPC1RAB9A
SCHEMBL8158480 0.71 CA12 (0.57) ALDH1A1KMT2ANPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 KDM4E 3720/4885ALDH1A1 326/4885CDC25B 119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.