SCHEMBL19082480

SCHEMBL19082480

CCOC(=O)c1ccc(Br)cc1-c1ccc2c(c1)oc1c3ccccc3ccc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
GAA P10253 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GLA P06280 1/20 0.47
ALOX5 P09917 6/20 0.46
TBK1 Q9UHD2 1/20 0.44
CDC25B P30305 1/20 0.41
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
RECQL P46063 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19084992 0.81 ALOX5 (0.48) ALDH1A1GAAKDM4EGLAALOX5
SCHEMBL17852149 0.81 SLC6A2 (0.52) ALDH1A1GAAKDM4EGLACDC25B
SCHEMBL19082510 0.78 KDM4E (0.40) ALDH1A1GAAKDM4EGLACDC25B
SCHEMBL17836985 0.76 CDC25B (0.54) ALDH1A1GAAKDM4EGLAALOX5
SCHEMBL11914433 0.76 KDM4E (0.57) ALDH1A1GAAKDM4EGLACDC25B
SCHEMBL19082479 0.75 CYP1A1 (0.38) ALDH1A1KDM4EALOX5KMT2ACYP1A2
SCHEMBL17852148 0.74 ALDH1A1 (0.49) ALDH1A1GAAKDM4EGLAALOX5
SCHEMBL18271472 0.73 MAOB (0.44) ALDH1A1KDM4EKMT2ACYP1A2CYP3A4
SCHEMBL16067566 0.73 KMT2A (0.45) ALDH1A1KDM4EKMT2ASMN1; SMN2CYP1A2
SCHEMBL29595884 0.73 KMT2A (0.45) ALDH1A1KDM4EKMT2ASMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 ALDH1A1 326/4885GAA 3736/4885KDM4E 3720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.