Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibemethine SCHEMBL10542007 | 0.79 | ALDH1A1 (0.70) | ALDH1A1KDM4ESMN1; SMN2KMT2ACARM1 | |
| Dibemethine SCHEMBL276863 | 0.79 | ALDH1A1 (0.70) | ALDH1A1KDM4ESMN1; SMN2KMT2ACARM1 | |
| SCHEMBL10194246 | 0.78 | CYP2C19 (0.61) | ALDH1A1KDM4ESMN1; SMN2CARM1PRMT6 | |
| SCHEMBL22305213 | 0.78 | KDM4E (0.61) | ALDH1A1KDM4ESMN1; SMN2CARM1PRMT6 | |
| Dibemethine SCHEMBL2139708 | 0.77 | ALDH1A1 (0.67) | ALDH1A1KDM4ESMN1; SMN2CARM1PRMT6 | |
| SCHEMBL7819859 | 0.74 | CALM1 (0.48) | ALDH1A1KDM4ETSHRCYP3A4 | |
| SCHEMBL25644510 | 0.74 | CYP11B1 (0.36) | SMN1; SMN2KMT2AMEN1HPGDLMNA | |
| SCHEMBL21509497 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL17193570 | 0.73 | ALDH1A1 (0.70) | ALDH1A1KDM4ESMN1; SMN2KMT2ACARM1 | |
| SCHEMBL7959943 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170191976-A1 | Method and Kit for Detecting Lead in a Solid Sample | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-07-06 | — | — | US | disclosed |
| US-20170191976-A1 | Method and Kit for Detecting Lead in a Solid Sample | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-07-06 | — | — | US | disclosed |