Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17274931 | 0.89 | ALDH1A1 (0.41) | SMN1; SMN2LMNAMAPTHPGDRAB9A | |
| SCHEMBL4226992 | 0.88 | ALDH1A1 (0.54) | LMNAALDH1A1SENP8SENP6PARP10 | |
| SCHEMBL17287080 | 0.87 | PARP10 (0.56) | ALDH1A1ESR1HSD17B10SENP8SENP6 | |
| SCHEMBL17287082 | 0.84 | ELANE (0.46) | ALDH1A1TSHRSTSKMT2A | |
| SCHEMBL17274951 | 0.80 | NAAA (0.39) | SMN1; SMN2CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL22288733 | 0.78 | TSHR (0.58) | LMNAALDH1A1ESR1HSD17B10TSHR | |
| SCHEMBL17287083 | 0.77 | SLC6A2 (0.50) | SMN1; SMN2LMNATSHRKMT2AHRH1 | |
| SCHEMBL17274956 | 0.77 | PKM (0.42) | SMN1; SMN2LMNAMAPTALDH1A1GAA | |
| SCHEMBL19147204 | 0.77 | ESR2 (0.42) | ESR1CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL17873483 | 0.77 | LMNA (0.61) | SMN1; SMN2LMNAMAPTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190874-A1 | Stabilizer Compounds | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190874-A1 | Stabilizer Compounds | HSF1, HEATR1, TBCA | SMN1; SMN2 590/4885LMNA 1511/4885MAPT 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.