Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23945710 | 0.98 | KDM4E (0.33) | KDM4EMAPK1HIF1A | |
| SCHEMBL20647303 | 0.98 | KDM4E (0.33) | KDM4EMAPK1HIF1A | |
| SCHEMBL21991783 | 0.98 | KDM4E (0.33) | KDM4EMAPK1HIF1A | |
| SCHEMBL23945983 | 0.98 | KDM4E (0.33) | KDM4EMAPK1HIF1A | |
| SCHEMBL26748315 | 0.87 | CA3 (0.32) | — | |
| SCHEMBL24429310 | 0.84 | SIGMAR1 (0.35) | — | |
| SCHEMBL19380753 | 0.80 | EPHX1 (0.46) | — | |
| SCHEMBL21891807 | 0.80 | KDM4E (0.36) | KDM4EMAPK1HIF1A | |
| SCHEMBL23945907 | 0.78 | EPHX1 (0.50) | — | |
| SCHEMBL20440154 | 0.78 | EPHX1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11197877-B2 | Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists | GLYCOMIMETICS. INC. (US) | 2021-12-14 | — | — | US | disclosed |
| US-20200129536-A1 | GALACTOPYRANOSYL-CYCLOHEXYL DERIVATIVES AS E-SELECTIN ANTAGONISTS | GLYCOMIMETICS, INC. (US) | 2020-04-30 | — | — | US | disclosed |
| WO-2019079701-A1 | HETEROBIFUNCTIONAL COMPOUNDS WITH IMPROVED SPECIFICITYFOR THE BROMODOMAIN OF BRD4 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-04-25 | — | — | WO | disclosed |
| US-10010562-B2 | Dual molecular delivery of oligonucleotides and peptide containing conjugates | MERCK SHARP & DOHME CORP. (US) | 2018-07-03 | — | — | US | disclosed |
| US-20170189441-A1 | DUAL MOLECULAR DELIVERY OF OLIGONUCLEOTIDES AND PEPTIDE CONTAINING CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10010562-B2 | Dual molecular delivery of oligonucleotides and peptide containing conjugates | DCLRE1A, DCLRE1B, LNPEP | KDM4E 4035/4885MAPK1 4115/4885HIF1A 1011/4885 |
| US-11197877-B2 | Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists | SELE, SELPLG, SELP | KDM4E 3860/4885MAPK1 3061/4885HIF1A 1715/4885 |
| US-20200129536-A1 | GALACTOPYRANOSYL-CYCLOHEXYL DERIVATIVES AS E-SELECTIN ANTAGONISTS | SELE, SELPLG, SELP | KDM4E 4586/4885MAPK1 2414/4885HIF1A 1671/4885 |
| US-20170189441-A1 | DUAL MOLECULAR DELIVERY OF OLIGONUCLEOTIDES AND PEPTIDE CONTAINING CONJUGATES | DCLRE1A, DCLRE1B, LNPEP | KDM4E 4035/4885MAPK1 4115/4885HIF1A 1011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.