SCHEMBL19084910

SCHEMBL19084910

O=C(Nc1ccc([SH](=O)=O)cc1)Nc1cccc(NC(=O)Oc2ccccc2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.57
ALDH1A1 P00352 6/20 0.55
MAPT P10636 5/20 0.55
KMT2A Q03164 3/20 0.55
RAD51 Q06609 1/20 0.54
KDM4E B2RXH2 2/20 0.52
GAA P10253 2/20 0.51
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MEN1 O00255 2/20 0.51
RAB9A P51151 2/20 0.51
BCHE P06276 2/20 0.51
THRB P10828 1/20 0.51
GFER P55789 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
ACHE P22303 1/20 0.51
TP53 P04637 2/20 0.50
LMNA P02545 1/20 0.50
NPC1 O15118 1/20 0.50
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17355405 0.92 CYP1A2 (0.66) CYP1A2ALDH1A1MAPTKMT2ARAD51
SCHEMBL13104404 0.86 CA12 (0.61) CYP1A2ALDH1A1MAPTKMT2ARAD51
SCHEMBL14174290 0.85 CYP1A2 (0.62) CYP1A2ALDH1A1MAPTKMT2ARAD51
SCHEMBL25680688 0.85 RAB9A (0.56) CYP1A2ALDH1A1MAPTKMT2ARAD51
SCHEMBL8048626 0.84 CYP1A2 (0.76) CYP1A2ALDH1A1MAPTKMT2ARAD51
SCHEMBL13104410 0.84 SIRT1 (0.68) CYP1A2ALDH1A1MAPTKMT2AMEN1
SCHEMBL13104408 0.84 RAB9A (0.58) CYP1A2ALDH1A1MAPTKMT2ARAD51
SCHEMBL17359771 0.83 CYP1A2 (0.56) CYP1A2ALDH1A1MAPTKMT2ARAD51
SCHEMBL18862216 0.82 ALDH1A1 (0.58) CYP1A2ALDH1A1MAPTKMT2ARAD51
SCHEMBL18885469 0.81 CYP1A2 (0.56) CYP1A2ALDH1A1MAPTKMT2ARAD51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230202220-A1 HEAT-SENSITIVE RECORDING MATERIAL KOEHLER INNOVATION & TECHNOLOGY GMBH (DE) 2023-06-29 US disclosed
US-20210331508-A1 HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2021-10-28 US disclosed
US-11084308-B2 Heat-sensitive recording material PAPIERFABRIK AUGUST KOEHLER SE (DE) 2021-08-10 US disclosed
EP-3730306-A1 NON-PHENOLIC COLOUR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL Papierfabrik August Koehler SE (DE) 2020-10-28 EP disclosed
US-20200172477-A1 NON-PHENOLIC COLOR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2020-06-04 US disclosed
EP-2957427-B1 HEAT-SENSITIVE RECORDING BODY OJI HOLDINGS CORP (JP) 2019-07-24 EP disclosed
US-10265985-B2 Heat-sensitive recording material PAPIERFABRIK AUGUST KOEHLER SE (DE) 2019-04-23 US disclosed
US-20190077178-A1 SELF-ADHESIVE, HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2019-03-14 US disclosed
US-20180079243-A1 HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2018-03-22 US disclosed
US-20170190199-A1 HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOHLER SE (DE) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172477-A1 NON-PHENOLIC COLOR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL TDO2, SCO2, SCN1A CYP1A2 55/4885ALDH1A1 312/4885MAPT 2275/4885
US-20210331508-A1 HEAT-SENSITIVE RECORDING MATERIAL SCN1A, KCNN2, SCN1B CYP1A2 36/4885ALDH1A1 130/4885MAPT 1260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.