Methane

Methane

SCHEMBL19084990

C.O.[SiH4]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Methane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL23235271 1.00
Methane SCHEMBL28677866 0.87
Methane SCHEMBL28886332 0.87
Methane SCHEMBL29030770 0.87
Methane SCHEMBL25421868 0.87
Methane SCHEMBL19205777 0.87
Methane SCHEMBL28839567 0.87
Methane SCHEMBL28731863 0.87
Methane SCHEMBL28689116 0.87
Methane SCHEMBL27970802 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11876233-B2 Thin film battery stacking INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2024-01-16 US claimed
US-11592394-B2 Methods and systems for transmission and detection of free radicals WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-02-28 US claimed
CN-115064577-A GaN-based heterojunction transverse Schottky diode and preparation method thereof 西安电子科技大学 2022-09-16 CN claimed
CN-113851466-B Isolation capacitor and preparation method thereof 北京智芯微电子科技有限公司 2022-03-22 CN claimed
CN-113851466-A Isolation capacitor and preparation method thereof 北京智芯微电子科技有限公司 2021-12-28 CN claimed
CN-113667976-A Corrosion-resistant DLC film with hole sealing top layer and preparation method thereof 中国科学院兰州化学物理研究所 2021-11-19 CN claimed
US-10957786-B2 FinFET with reduced extension resistance and methods of manufacturing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-03-23 US claimed
US-10930768-B2 Low current leakage finFET and methods of making the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-02-23 US claimed
US-20200127125-A1 LOW CURRENT LEAKAGE FINFET AND METHODS OF MAKING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-04-23 US claimed
US-20200127123-A1 FINFET WITH REDUCED EXTENSION RESISTANCE AND METHODS OF MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-04-23 US claimed
CN-105293500-B A kind of preparation method of silica carbon aerogels 天津大学 2018-01-12 CN claimed
US-9700872-B1 Superpolar chromatographic stationary phases and extraction sorbents and their methods of synthesis THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2017-07-11 US claimed
CN-106609055-A Baking varnish 天津市新丽华色材有限责任公司 2017-05-03 CN claimed
CN-103805983-A Surface treatment method for permanent magnet material by adopting phosphorization agent to carry out phosphorization treatment BEIJING ZHONG KE SAN HUAN 2014-05-21 CN claimed
CN-101483171-B Airgap-containing interconnect structure with patternable low-K material and method of fabricating IBM 2011-04-06 CN claimed
CN-100552890-C The method of electronic structure and formation deielectric-coating IBM (US) 2009-10-21 CN claimed
CN-101483171-A Airgap-containing interconnect structure with patternable low-K material and method of fabricating IBM (US) 2009-07-15 CN claimed
CN-100485004-C Ink composition for ink jet recording SEIKO EPSON CORP (JP) 2009-05-06 CN claimed
CN-101101875-A Electronic structure and method for forming medium film IBM (US) 2008-01-09 CN claimed
CN-1807525-A Ink composition for ink jet recording SEIKO EPSON CORP (JP) 2006-07-26 CN claimed