SCHEMBL8746480

SCHEMBL8746480

O=S(=O)(O)c1cc(-n2nc3ccc4ccccc4c3n2)ccc1C=Cc1ccccc1.[Na]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.46
SENP2 Q9HC62 3/20 0.42
SENP1 Q9P0U3 3/20 0.42
SUMO2 P61956 2/20 0.42
SUMO1 P63165 2/20 0.42
SENP7 Q9BQF6 2/20 0.42
SENP3 Q9H4L4 2/20 0.42
KDM4E B2RXH2 1/20 0.36
GFER P55789 1/20 0.35
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
KLK7 P49862 1/20 0.35
KMT2A Q03164 1/20 0.35
TP53 P04637 2/20 0.35
LMNA P02545 1/20 0.35
SLC16A3 O15427 1/20 0.34
ENPP2 Q13822 1/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NQO2 P16083 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31315043 1.00 ALOX5 (0.46) ALOX5SENP2SENP1SUMO2SUMO1
SCHEMBL31588309 0.99 ALOX5 (0.46) ALOX5SENP2SENP1SUMO2SUMO1
SCHEMBL1033597 0.99 ALOX5 (0.46) ALOX5SENP2SENP1SUMO2SUMO1
SCHEMBL1033598 0.99 ALOX5 (0.46) ALOX5SENP2SENP1SUMO2SUMO1
SCHEMBL3910081 0.98 ALOX5 (0.46) ALOX5SENP2SENP1SUMO2SUMO1
SCHEMBL3910090 0.98 ALOX5 (0.46) ALOX5SENP2SENP1SUMO2SUMO1
SCHEMBL13220658 0.94 ALOX5 (0.51) ALOX5SENP2SENP1SUMO2SUMO1
SCHEMBL12994686 0.89 ALOX5 (0.39) ALOX5SENP2SENP1SUMO2SUMO1
SCHEMBL3910085 0.88 ALOX5 (0.46) ALOX5SENP2SENP1SUMO2SUMO1
SCHEMBL1502431 0.88 ALOX5 (0.46) ALOX5SENP2SENP1SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023073729-A1 A SEALANT COMPOSITION FOR SUBSTRATES SAINT-GOBAIN GLASS FRANCE (FR) 2023-05-04 WO claimed
US-20200032171-A1 Laundry Method, Use of Polypeptide and Detergent Composition NOVOZYMES A/S (DK) 2020-01-30 US claimed
EP-0237119-B2 Stable liquid detergent composition containing hydrophobic brightener PROCTER & GAMBLE (US) 1997-02-19 EP claimed
EP-3607038-B1 CLEANING COMPOSITIONS AND USES THEREOF NOVOZYMES AS (DK) 2026-05-06 EP disclosed
EP-3708660-B1 POLYPEPTIDES NOVOZYMES AS (DK) 2026-04-29 EP disclosed
EP-3704220-B1 METHODS FOR CLEANING MEDICAL DEVICES NOVOZYMES AS (DK) 2026-04-15 EP disclosed
US-12590273-B2 Stabilized glycoside hydrolase variants NOVOZYMES A/S (DK) 2026-03-31 US disclosed
US-20260078359-A1 POLYPEPTIDES NOVOZYMES A/S (DK) 2026-03-19 US disclosed
EP-4077617-B1 STABILIZED LIQUID BORON-FREE ENZYME COMPOSITIONS NOVOZYMES AS (DK) 2026-03-18 EP disclosed
US-12516273-B2 Glycosyl hydrolases NOVOZYMES A/S (DK) 2026-01-06 US disclosed
US-12509645-B2 Cleaning compositions and uses thereof NOVOZYMES A/S (DK) 2025-12-30 US disclosed
US-20150299622-A1 Enzyme Compositions Enabling Re-use of Water in Laundry NOVOZYMES AS (DK) 2015-10-22 US disclosed
WO-2015150457-A1 POLYPEPTIDES HAVING ALPHA AMYLASE ACTIVITY NOVOZYMES A/S (DK) 2015-10-08 WO disclosed
WO-2015144561-A1 LIQUID DETERGENT COMPOSITIONS COMPRISING AN ALPHA-AMYLASE UNILEVER N.V. (NL) 2015-10-01 WO disclosed
US-20150184208-A1 ENZYMATIC REDUCTION OF HYDROPEROXIDES NOVOZYMES A/S (DK) 2015-07-02 US disclosed
EP-2799533-A1 Protease and inhibitor containing water-soluble films Novozymes A/S (DK) 2014-11-05 EP disclosed
US-20140227738-A1 Polypeptides Having Protease Activity and Polynucleotides Encoding Same NOVOZYMES A/S (DK) 2014-08-14 US disclosed
EP-2366009-B1 LAUNDRY COMPOSITIONS UNILEVER PLC (GB) 2012-10-24 EP disclosed
CN-102574996-A Improvements to laundry compositions UNILEVER PLC 2012-07-11 CN disclosed
CN-102575203-A Improvements in Laundry Compositions UNILEVER PLC 2012-07-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509645-B2 Cleaning compositions and uses thereof UNG, DNASE1, OGG1 ALOX5 2526/4885SENP2 1760/4885SENP1 1268/4885
US-12590273-B2 Stabilized glycoside hydrolase variants IDUA, IDE, TREH ALOX5 3981/4885SENP2 201/4885SENP1 99/4885
US-20260078359-A1 POLYPEPTIDES IDUA, IDE, AGL ALOX5 3273/4885SENP2 956/4885SENP1 839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.