Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19034541 | 0.85 | DNM1 (0.36) | DNM1ALDH1A1TSHRMAPTTDP1 | |
| SCHEMBL21698588 | 0.83 | ALDH1A1 (0.41) | DNM1ALDH1A1TSHRMAPTPAOX | |
| SCHEMBL21698552 | 0.81 | DNM1 (0.44) | DNM1ALDH1A1TSHRMAPT | |
| SCHEMBL4791412 | 0.79 | DNM1 (0.48) | DNM1ALDH1A1TSHR | |
| SCHEMBL170759 | 0.79 | DNM1 (0.48) | DNM1ALDH1A1TSHR | |
| SCHEMBL3810882 | 0.76 | — | — | |
| SCHEMBL21698745 | 0.76 | ALDH1A1 (0.46) | DNM1ALDH1A1TSHRPAOX | |
| SCHEMBL73471 | 0.76 | — | — | |
| SCHEMBL25039586 | 0.76 | DNM1 (0.40) | DNM1ALDH1A1TSHRLSS | |
| SCHEMBL140921 | 0.74 | CES2 (0.46) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017117528-A1 | LIPIDS AND LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDS | Acuitas Therapeutics, Inc. (CA) | 2017-07-06 | — | — | WO | disclosed |