Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.52 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.47 |
| ▸ | TEK | Q02763 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038205 | 0.85 | NAMPT (0.60) | HSP90AB1NAMPTHDAC3HDAC4HDAC1 | |
| SCHEMBL16068261 | 0.82 | KEAP1 (0.53) | HSP90AB1NAMPTMEN1KMT2A | |
| SCHEMBL16068165 | 0.81 | TEK (0.53) | UCHL5NAMPTHDAC3HDAC4HDAC1 | |
| SCHEMBL460447 | 0.79 | TEK (0.55) | UCHL5NAMPTHDAC3HDAC4HDAC1 | |
| SCHEMBL16155169 | 0.76 | HDAC3 (0.54) | UCHL5NAMPTHDAC3HDAC4HDAC1 | |
| SCHEMBL14987759 | 0.76 | TEK (0.55) | UCHL5HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16155361 | 0.75 | HDAC3 (0.56) | UCHL5NAMPTHDAC3HDAC4HDAC1 | |
| SCHEMBL16155356 | 0.74 | HDAC3 (0.53) | UCHL5NAMPTHDAC3HDAC4HDAC1 | |
| SCHEMBL30722374 | 0.73 | TEK (0.57) | UCHL5TEKKDRMEN1KMT2A | |
| SCHEMBL16264699 | 0.73 | TEK (0.57) | UCHL5TEKKDRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017118690-A1 | A NOVEL SYNTHETIC PATHWAY TOWARDS SOLITHROMYCIN AND PURIFICATION THEREOF | LEK PHARMACEUTICALS D.D. (SI) | 2017-07-13 | — | — | WO | disclosed |
| EP-3190122-A1 | A NOVEL SYNTHETIC PATHWAY TOWARDS SOLITHROMYCIN AND PURIFICATION THEREOF | LEK Pharmaceuticals d.d. (SI) | 2017-07-12 | — | — | EP | disclosed |