SCHEMBL19086435

SCHEMBL19086435

COC(=O)C(Br)c1ccc(OC(=O)CCCBr)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.50
HSD17B10 Q99714 2/20 0.50
ALDH1A1 P00352 2/20 0.50
MAPT P10636 2/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50
ESR1 P03372 1/20 0.44
HIF1A Q16665 1/20 0.44
MEN1 O00255 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
EGFR P00533 1/20 0.38
ERBB2 P04626 1/20 0.38
SLC22A2 O15244 1/20 0.36
TMPRSS2 O15393 1/20 0.36
F2 P00734 1/20 0.36
F10 P00742 1/20 0.36
PLG P00747 1/20 0.36
F12 P00748 1/20 0.36
PLAU P00749 1/20 0.36
PLAT P00750 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19470771 0.93 KMT2A (0.51) KMT2AHSD17B10ALDH1A1MAPTLMNA
SCHEMBL28886327 0.81 L3MBTL1 (0.46) KMT2AMAPTHTTMEN1SMN1; SMN2
SCHEMBL1969461 0.79 LMNA (0.48) KMT2AHSD17B10ALDH1A1MAPTLMNA
SCHEMBL19086434 0.77 ELANE (0.42) KMT2AHSD17B10ALDH1A1MAPTLMNA
SCHEMBL5556095 0.77 SMN1; SMN2 (0.50) KMT2AMAPTMEN1SMN1; SMN2FAAH
SCHEMBL378101 0.76 KMT2A (0.49) KMT2AALDH1A1HTTMEN1SMN1; SMN2
SCHEMBL5551276 0.75 LTA4H (0.48) KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL19086385 0.75 KMT2A (0.59) KMT2AHSD17B10ALDH1A1MAPTLMNA
SCHEMBL9000712 0.75 SMN1; SMN2 (0.57) LMNAHIF1ASMN1; SMN2CYP1A2CYP2D6
SCHEMBL20484981 0.74 ACACB (0.50) KMT2AALDH1A1LMNAMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3190131-B1 LIVING RADICAL POLYMERIZATION INITIATOR, METHOD FOR PRODUCING POLYMER, AND POLYMER UNIV KYOTO (JP) 2020-07-29 EP disclosed
US-10414848-B2 Living radical polymerization initiator, method for producing polymer, and polymer KYOTO UNIVERSITY (JP) 2019-09-17 US disclosed
US-20170306073-A1 LIVING RADICAL POLYMERIZATION INITIATOR, METHOD FOR PRODUCING POLYMER, AND POLYMER KYOTO UNIVERSITY (JP) 2017-10-26 US disclosed
EP-3190131-A1 LIVING RADICAL POLYMERIZATION INITIATOR, METHOD FOR PRODUCING POLYMER, AND POLYMER Kyoto University (JP) 2017-07-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10414848-B2 Living radical polymerization initiator, method for producing polymer, and polymer CCNY, MTR, PARN KMT2A 453/4885HSD17B10 3157/4885ALDH1A1 2596/4885
US-20170306073-A1 LIVING RADICAL POLYMERIZATION INITIATOR, METHOD FOR PRODUCING POLYMER, AND POLYMER CCNY, MTR, PARN KMT2A 453/4885HSD17B10 3157/4885ALDH1A1 2596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.