Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22320285 | 0.88 | ACHE (0.33) | CSF1RACHEHIF1AMEN1USP2 | |
| SCHEMBL10076681 | 0.87 | L3MBTL1 (0.39) | CSF1RHIF1AMEN1USP2ALDH1A1 | |
| SCHEMBL21410221 | 0.84 | EGFR (0.39) | EGFRUCHL1 | |
| SCHEMBL2280832 | 0.84 | SNCA (0.38) | HIF1AALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL31652177 | 0.84 | LPL (0.40) | EGFRLPLLIPG | |
| SCHEMBL30973537 | 0.84 | EGFR (0.39) | EGFRUCHL1 | |
| SCHEMBL3804868 | 0.83 | SNCA (0.37) | HIF1AALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL3804866 | 0.83 | SNCA (0.37) | HIF1AALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL15334799 | 0.83 | ACHE (0.47) | CSF1RACHEMEN1USP2ALDH1A1 | |
| SCHEMBL22712518 | 0.82 | EGFR (0.43) | HIF1AALDH1A1MAPTMAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969920-A | Fused pyridazine derivative, preparation method and medical application thereof | 上海辉启生物医药科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| EP-3921311-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | Skyhawk Therapeutics, Inc. (US) | 2021-12-15 | — | — | EP | disclosed |
| WO-2020163647-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2020-08-13 | — | — | WO | disclosed |
| US-10562858-B2 | Crystalline anti-trichophyton agents and preparation process thereof | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2020-02-18 | — | — | US | disclosed |
| US-20170233346-A1 | CRYSTALLINE ANTI-TRICHOPHYTON AGENTS AND PREPARATION PROCESS THEREOF | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2017-08-17 | — | — | US | disclosed |
| EP-3190105-A1 | CRYSTALLINE ANTI-TRICHOPHYTON DRUG AND METHOD FOR PRODUCING SAME | Meiji Seika Pharma Co., Ltd. (JP) | 2017-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562858-B2 | Crystalline anti-trichophyton agents and preparation process thereof | ZP1, TBKBP1, MITF | CSF1R 3176/4885ACHE 4734/4885HIF1A 2682/4885 |
| US-20170233346-A1 | CRYSTALLINE ANTI-TRICHOPHYTON AGENTS AND PREPARATION PROCESS THEREOF | ZP1, TBKBP1, MITF | CSF1R 3176/4885ACHE 4734/4885HIF1A 2682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.