Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 6/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19087012 | 0.84 | HCRTR2 (0.39) | KDM1AHDAC6PRMT5WDR77CCNC | |
| SCHEMBL19086240 | 0.82 | EGFR (0.43) | KDM1AHDAC6PRMT5WDR77HTT | |
| SCHEMBL19086202 | 0.81 | KDM1A (0.48) | KDM1AHDAC6PRMT5WDR77HTT | |
| SCHEMBL19086189 | 0.77 | PRMT5 (0.48) | KDM1AHDAC6PRMT5WDR77HTT | |
| SCHEMBL19086245 | 0.77 | HDAC6 (0.43) | KDM1AHDAC6PRMT5WDR77HTT | |
| SCHEMBL19086176 | 0.76 | KDM1A (0.51) | KDM1AHDAC6PRMT5WDR77SMN1; SMN2 | |
| SCHEMBL19086218 | 0.75 | KDM1A (0.48) | KDM1AHDAC6PRMT5WDR77HTT | |
| SCHEMBL19086347 | 0.75 | KDM1A (0.46) | KDM1AHDAC6PRMT5WDR77HTT | |
| SCHEMBL19086315 | 0.74 | KDM1A (0.47) | KDM1AHDAC6PRMT5WDR77ALDH1A1 | |
| SCHEMBL19087005 | 0.74 | KDM1A (0.41) | KDM1AHDAC6PRMT5WDR77HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114275-A1 | COMPOUND FOR INHIBITING ROCK, PREPARATION METHOD AND USE OF SAME | 成都先导药物开发有限公司 | 2017-07-06 | — | — | WO | disclosed |