Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FABP7 | O15540 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19088520 | 0.81 | TDP1 (0.48) | MGLLFAAHALDH1A1TDP1BRD4 | |
| SCHEMBL21159519 | 0.68 | BRD4 (0.41) | ALDH1A1BRD4NPSR1FABP7 | |
| SCHEMBL30730411 | 0.66 | LIPE (0.46) | ALDH1A1BRD4SMN1; SMN2LMNA | |
| SCHEMBL28772305 | 0.65 | BTK (0.33) | BRD4FABP7 | |
| SCHEMBL22570504 | 0.64 | LTA4H (0.42) | BRD4 | |
| SCHEMBL21266633 | 0.63 | AAK1 (0.35) | BRD4FABP7 | |
| SCHEMBL19088521 | 0.63 | L3MBTL1 (0.38) | TDP1BRD4FABP7 | |
| SCHEMBL19088511 | 0.63 | BRD4 (0.37) | BRD4NPSR1FABP7 | |
| SCHEMBL23279538 | 0.63 | LTA4H (0.40) | ALDH1A1BRD4LMNANPSR1FABP7 | |
| SCHEMBL29551187 | 0.63 | TDP1 (0.47) | MGLLFAAHALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116702-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2017-07-06 | — | — | WO | disclosed |