Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MGLL | Q99685 | 4/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21159519 | 0.83 | BRD4 (0.41) | ALDH1A1MAPK1BRD4MEN1KMT2A | |
| SCHEMBL19088519 | 0.81 | MGLL (0.36) | TDP1ALDH1A1MGLLFAAHSMN1; SMN2 | |
| SCHEMBL23279538 | 0.80 | LTA4H (0.40) | ALDH1A1MAPK1L3MBTL1BRD4KDM4E | |
| SCHEMBL18256350 | 0.80 | LTA4H (0.40) | ALDH1A1MAPK1L3MBTL1BRD4KDM4E | |
| SCHEMBL3708328 | 0.79 | TDP1 (0.66) | TDP1ALDH1A1MGLLFAAHMAPK1 | |
| SCHEMBL19088521 | 0.79 | L3MBTL1 (0.38) | TDP1MAPK1L3MBTL1BRD4MEN1 | |
| SCHEMBL29551187 | 0.78 | TDP1 (0.47) | TDP1ALDH1A1MGLLFAAHMAPK1 | |
| SCHEMBL23279516 | 0.77 | PPARG (0.41) | ALDH1A1BRD4MEN1KMT2ANPSR1 | |
| SCHEMBL304176 | 0.77 | TDP1 (0.78) | TDP1ALDH1A1MAPK1L3MBTL1APP | |
| SCHEMBL24297636 | 0.77 | FABP7 (0.39) | MAPK1L3MBTL1BRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397638-B1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2017116702-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2017-07-06 | — | — | WO | disclosed |