Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 2/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19088919 | 0.91 | PDE4D (0.34) | TAS1R3TAS1R1TAS1R2PDE10APDCD1 | |
| SCHEMBL19088918 | 0.90 | PDE4D (0.34) | TAS1R3TAS1R1TAS1R2PDE10APDCD1 | |
| SCHEMBL17899031 | 0.90 | HPGDS (0.31) | HPGDS | |
| SCHEMBL19088921 | 0.89 | RIPK1 (0.36) | TAS1R3TAS1R1TAS1R2RIPK1PDE4A | |
| SCHEMBL17898894 | 0.89 | HPGDS (0.32) | TAS1R3TAS1R1TAS1R2RIPK1ROCK1 | |
| SCHEMBL17898692 | 0.89 | HPGDS (0.30) | HPGDS | |
| SCHEMBL19088924 | 0.88 | PDE4D (0.36) | RIPK1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19084243 | 0.88 | TAS1R3 (0.37) | TAS1R3TAS1R1TAS1R2PDE10AKMT2A | |
| SCHEMBL19089232 | 0.88 | RIPK1 (0.32) | RIPK1ROCK1ROCK2PDE10APDCD1 | |
| SCHEMBL17899036 | 0.88 | ROCK1 (0.31) | TAS1R3TAS1R1RIPK1ROCK1PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116949-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | WO | disclosed |