SCHEMBL19097697

SCHEMBL19097697

FC(F)(F)c1ccc([Si](F)(F)F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.50
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
ORAI1 Q96D31 1/20 0.44
ORAI2 Q96SN7 1/20 0.44
ORAI3 Q9BRQ5 1/20 0.44
TRPV6 Q9H1D0 1/20 0.44
MGLL Q99685 1/20 0.44
TAAR1 Q96RJ0 1/20 0.41
EPHX2 P34913 1/20 0.39
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
PLAU P00749 1/20 0.39
HTR3A P46098 1/20 0.39
HTR3D Q70Z44 1/20 0.39
HTR3C Q8WXA8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL63468 0.80 ALDH1A1 (0.67) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL12773794 0.80 NR1H2 (0.60) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL24032707 0.79 KIF11 (0.52) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL1052798 0.74 KIF11 (0.48) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL3175501 0.74 KIF11 (0.48) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL9226183 0.74 NR1H2 (0.50) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL11416439 0.74 KIF11 (0.48) KIF11ALDH1A1TSHRCES2CES1
SCHEMBL15733461 0.74 KIF11 (0.48) KIF11ALDH1A1TSHRCES2CES1
Iodide SCHEMBL29093539 0.74 ALDH1A1 (0.59) KIF11ALDH1A1TSHRCES2CES1
Bromide SCHEMBL29093544 0.74 ALDH1A1 (0.59) KIF11ALDH1A1TSHRCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9880479-B2 Toner, toner stored unit, image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2018-01-30 US disclosed
US-20170199476-A1 TONER, TONER STORED UNIT, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2017-07-13 US disclosed