SCHEMBL15733461

SCHEMBL15733461

O[Si](O)(O)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.48
TRPV6 Q9H1D0 2/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
ORAI1 Q96D31 1/20 0.48
ORAI2 Q96SN7 1/20 0.48
ORAI3 Q9BRQ5 1/20 0.48
MGLL Q99685 1/20 0.48
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
EPHX2 P34913 1/20 0.43
HTR3E A5X5Y0 1/20 0.43
HTR3B O95264 1/20 0.43
PLAU P00749 1/20 0.43
HTR3A P46098 1/20 0.43
HTR3D Q70Z44 1/20 0.43
HTR3C Q8WXA8 1/20 0.43
SRD5A2 P31213 1/20 0.41
GSK3B P49841 2/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15735661 0.93 KIF11 (0.60) KIF11TRPV6CES2CES1ORAI1
SCHEMBL11416439 0.83 KIF11 (0.48) KIF11TRPV6CES2CES1ORAI1
SCHEMBL18691999 0.79 NR1H2 (0.45) KIF11TRPV6CES2CES1ORAI1
SCHEMBL63468 0.78 ALDH1A1 (0.67) KIF11TRPV6CES2CES1ORAI1
SCHEMBL272403 0.78 ESR1 (0.30)
SCHEMBL1052798 0.78 KIF11 (0.48) KIF11TRPV6CES2CES1ORAI1
SCHEMBL15736807 0.77 RXRA (0.56) KIF11CES2
SCHEMBL24032707 0.77 KIF11 (0.52) KIF11TRPV6CES2CES1ORAI1
SCHEMBL15737011 0.76 CES2 (0.46) KIF11CES2ALDH1A1TSHR
SCHEMBL19097697 0.74 KIF11 (0.50) KIF11TRPV6CES2CES1ORAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed