Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PPID | Q08752 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876031 | 0.94 | LOXL2 (0.34) | LOXL2MAOAMAOBHTTEPHX1 | |
| SCHEMBL19763309 | 0.94 | LOXL2 (0.34) | LOXL2MAOAMAOBHTTEPHX1 | |
| SCHEMBL19084672 | 0.92 | ACHE (0.39) | LOXL2MAOAMAOBALDH1A1TDP1 | |
| SCHEMBL19099649 | 0.87 | KMT2A (0.41) | EPHX1ALDH1A1PPIDHDAC6HDAC8 | |
| SCHEMBL19365160 | 0.86 | HDAC3 (0.30) | MAOAMAOBHDAC6HDAC8HDAC3 | |
| SCHEMBL22236839 | 0.82 | MEN1 (0.43) | HTTEPHX1ALDH1A1TDP1MAPT | |
| SCHEMBL15928065 | 0.81 | IDO1 (0.39) | CYP3A4TSHRTDP1MAPT | |
| SCHEMBL15929444 | 0.81 | KDM1A (0.43) | HTT | |
| SCHEMBL15928040 | 0.79 | HDAC3 (0.35) | ALDH1A1MAPTLMNARECQLCNR2 | |
| SCHEMBL22236838 | 0.79 | MEN1 (0.38) | HTTEPHX1ALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170189567-A1 | Cage-Like Bifunctional Chelators, Copper-64 Radiopharmaceuticals and PET Imaging Using the Same | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189567-A1 | Cage-Like Bifunctional Chelators, Copper-64 Radiopharmaceuticals and PET Imaging Using the Same | AOC1, MUSK, CTRC | LOXL2 3548/4885MAOA 704/4885MAOB 1426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.