Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19817096 | 0.85 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPK1LMNAHPGD | |
| SCHEMBL24088364 | 0.74 | KIF11 (0.33) | HPGDCASP1HSD17B10 | |
| SCHEMBL20637698 | 0.74 | KDM4E (0.47) | KDM4EPDGFRBMGLLGPR3ALDH1A1 | |
| SCHEMBL23656228 | 0.72 | KDM4E (0.41) | KDM4EMGLLGPR3ALDH1A1LMNA | |
| SCHEMBL21972250 | 0.70 | PDGFRB (0.46) | KDM4EPDGFRBMAPK1LMNAHTT | |
| SCHEMBL993337 | 0.70 | PDGFRB (0.64) | KDM4EPDGFRBALDH1A1LMNAGAA | |
| SCHEMBL29403090 | 0.70 | PDGFRB (0.64) | KDM4EPDGFRBALDH1A1LMNAGAA | |
| SCHEMBL21970634 | 0.69 | LMNA (0.59) | KDM4EPDGFRBMGLLALDH1A1LMNA | |
| SCHEMBL21971004 | 0.69 | PDGFRB (0.53) | KDM4EPDGFRBALDH1A1MAPK1LMNA | |
| SCHEMBL20120136 | 0.68 | HTR1A (0.40) | MGLLALDH1A1MAPK1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10800874-B2 | Poly(phenylene) and m-Terphenyl as protecting groups for benzimidazolium hydroxides | SIMON FRASER UNIVERSITY (CA) | 2020-10-13 | — | — | US | disclosed |
| US-10800874-B2 | Poly(phenylene) and m-Terphenyl as protecting groups for benzimidazolium hydroxides | SIMON FRASER UNIVERSITY (CA) | 2020-10-13 | — | — | US | disclosed |
| US-20190016851-A1 | POLY(PHENYLENE) AND M-TERPHENYL AS PROTECTING GROUPS FOR BENZIMIDAZOLIUM HYDROXIDES | SIMON FRASER UNIVERSITY (CA) | 2019-01-17 | — | — | US | disclosed |
| US-20190016851-A1 | POLY(PHENYLENE) AND M-TERPHENYL AS PROTECTING GROUPS FOR BENZIMIDAZOLIUM HYDROXIDES | SIMON FRASER UNIVERSITY (CA) | 2019-01-17 | — | — | US | disclosed |
| EP-3400215-A1 | POLY(PHENYLENE) AND M-TERPHENYL AS PROTECTING GROUPS FOR BENZIMIDAZOLIUM HYDROXIDES | Simon Fraser University (CA) | 2018-11-14 | — | — | EP | disclosed |
| WO-2017117678-A1 | POLY(PHENYLENE) AND M-TERPHENYL AS PROTECTING GROUPS FOR BENZIMIDAZOLIUM HYDROXIDES | SIMON FRASER UNIVERSITY (CA) | 2017-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190016851-A1 | POLY(PHENYLENE) AND M-TERPHENYL AS PROTECTING GROUPS FOR BENZIMIDAZOLIUM HYDROXIDES | H1-4, PNMT, H1-0 | KDM4E 927/4885PDGFRB 4511/4885MGLL 580/4885 |
| US-10800874-B2 | Poly(phenylene) and m-Terphenyl as protecting groups for benzimidazolium hydroxides | H1-4, PNMT, H1-0 | KDM4E 927/4885PDGFRB 4511/4885MGLL 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.