Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939276 | 0.69 | ALDH1A1 (0.47) | MEN1KMT2A | |
| SCHEMBL31468333 | 0.67 | PGR (0.47) | KMT2A | |
| SCHEMBL29190982 | 0.67 | GPR35 (0.37) | MEN1KMT2APOLB | |
| SCHEMBL6900293 | 0.66 | L3MBTL1 (0.38) | MEN1KMT2APOLB | |
| SCHEMBL1607511 | 0.66 | RAB9A (0.42) | MEN1KMT2A | |
| SCHEMBL2304428 | 0.65 | GSK3B (0.56) | MEN1KMT2A | |
| SCHEMBL3164617 | 0.63 | POLB (0.39) | EGLN1MEN1KMT2APOLB | |
| SCHEMBL2638367 | 0.63 | DAO (0.42) | MEN1KMT2APOLB | |
| SCHEMBL31352237 | 0.62 | HTT (0.52) | — | |
| SCHEMBL25214174 | 0.62 | ESR2 (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701686-B2 | Tricyclopyrazole derivatives | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2017-07-11 | — | — | US | disclosed |