Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | HRH2 | P25021 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13730333 | 0.90 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL14286498 | 0.89 | APEX1 (0.34) | — | |
| SCHEMBL14472607 | 0.89 | — | — | |
| SCHEMBL18862484 | 0.84 | HRH2 (0.41) | SMN1; SMN2ALDH1A1MAPTTHRBTHRA | |
| SCHEMBL23619608 | 0.82 | THRB (0.33) | MAPTTHRBTHRAHRH2HRH1 | |
| SCHEMBL15314276 | 0.82 | SMN1; SMN2 (0.35) | SMN1; SMN2MAPTLMNACYP2D6HRH3 | |
| SCHEMBL21125866 | 0.82 | HRH2 (0.40) | SMN1; SMN2ALDH1A1MAPTTHRBHRH2 | |
| SCHEMBL674334 | 0.79 | ALDH1A1 (0.46) | SMN1; SMN2TP53ALDH1A1MAPTTHRB | |
| SCHEMBL419258 | 0.79 | ALDH1A1 (0.46) | SMN1; SMN2TP53ALDH1A1MAPTTHRB | |
| SCHEMBL12788551 | 0.79 | LMNA (0.41) | SMN1; SMN2TP53ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700627-B2 | Biodegradable poly (beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-11 | — | — | US | disclosed |