SCHEMBL19103106

SCHEMBL19103106

c1ccc(-c2cccc3c2oc2c(N(c4ccccc4)c4cc5ccccc5c5ccccc45)cccc23)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRKDC P78527 5/20 0.34
▸ KDM4E B2RXH2 4/20 0.34
▸ MEN1 O00255 3/20 0.34
▸ KMT2A Q03164 3/20 0.34
▸ GPR84 Q9NQS5 3/20 0.34
▸ ALDH1A1 P00352 5/20 0.34
▸ PIK3CD O00329 3/20 0.34
▸ PIK3CA P42336 3/20 0.34
▸ PIK3CB P42338 3/20 0.34
▸ PIK3CG P48736 3/20 0.34
▸ BRD4 O60885 2/20 0.34
▸ BRD2 P25440 2/20 0.34
▸ BRD3 Q15059 2/20 0.34
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ TSHR P16473 2/20 0.34
▸ HIF1A Q16665 2/20 0.34
▸ HSD17B10 Q99714 2/20 0.34
▸ PDE2A O00408 1/20 0.34
▸ PIK3C2A O00443 1/20 0.34
▸ PIK3R2 O00459 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17703158 0.95 GPR84 (0.36) PRKDCKDM4EMEN1KMT2AGPR84
SCHEMBL18841418 0.94 PRKDC (0.36) PRKDCKDM4EMEN1KMT2AGPR84
SCHEMBL17737661 0.94 PRKDC (0.36) PRKDCKDM4EMEN1KMT2AGPR84
SCHEMBL24327245 0.93 CA12 (0.35) PRKDCKDM4EMEN1KMT2AGPR84
SCHEMBL24585464 0.93 KDM4E (0.36) PRKDCKDM4EMEN1KMT2AGPR84
SCHEMBL17703117 0.92 GPR84 (0.38) PRKDCKDM4EMEN1KMT2AGPR84
SCHEMBL16185382 0.92 PRKDC (0.37) PRKDCKDM4EMEN1KMT2AALDH1A1
SCHEMBL24585983 0.91 MEN1 (0.35) PRKDCKDM4EMEN1KMT2AGPR84
SCHEMBL17703133 0.91 GPR84 (0.39) PRKDCKDM4EMEN1KMT2AGPR84
SCHEMBL17703109 0.91 ALOX5 (0.36) PRKDCKDM4EMEN1KMT2AGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11329230-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-10 — — US disclosed
US-11316125-B2 Organic light-emitting device and display apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-26 — — US disclosed
US-20210119135-A1 LUMINESCENCE DEVICE AND AMINE COMPOUND FOR LUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-04-22 — — US disclosed
US-20200111986-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2020-04-09 — — US disclosed
EP-3246963-A2 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-11-22 — — EP disclosed
US-20170317294-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-02 — — US disclosed
US-20170317294-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-02 — — US disclosed
EP-3193384-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-07-19 — — EP disclosed
US-20170200899-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-13 — — US disclosed
US-20170200899-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11329230-B2 Organic light-emitting device EML4, SUN2, TRPA1 PRKDC 3792/4885KDM4E 2540/4885MEN1 2816/4885
US-20210119135-A1 LUMINESCENCE DEVICE AND AMINE COMPOUND FOR LUMINESCENCE DEVICE SLC18A1, SLC29A1, SAT1 PRKDC 4224/4885KDM4E 2048/4885MEN1 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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