Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1257364 | 0.96 | GABRA1 (0.52) | GABRA1GABRB2HSD17B1CYP1A2APP | |
| SCHEMBL20684744 | 0.87 | APP (0.41) | GABRA1GABRB2HSD17B1CYP1A2APP | |
| SCHEMBL5558364 | 0.87 | CYP1A2 (0.55) | GABRA1GABRB2HSD17B1CYP1A2APP | |
| SCHEMBL12247921 | 0.87 | HSD17B1 (0.46) | GABRA1GABRB2HSD17B1CYP1A2ESR1 | |
| SCHEMBL9446145 | 0.80 | EGFR (0.44) | CYP1A2 | |
| SCHEMBL31028402 | 0.78 | AMY1A (0.53) | MEN1GAAMAPTKMT2APKM | |
| SCHEMBL12035986 | 0.78 | AMY1A (0.53) | MEN1GAAMAPTKMT2APKM | |
| SCHEMBL14230974 | 0.77 | TSHR (0.45) | CYP1A2MEN1POLBMAPTKMT2A | |
| SCHEMBL9982981 | 0.77 | ANO1 (0.39) | MEN1POLBGAAMAPTKMT2A | |
| SCHEMBL239755 | 0.77 | ESR1 (0.48) | GABRA1GABRB2BACE1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3190107-B1 | ARYL COMPOUND SUBSTITUTED WITH GLYCIDYL AND ALLYL GROUPS AS MACROMONOMER FOR HEAT RESISTANT RESIN MATERIALS | SHINETSU CHEMICAL CO (JP) | 2019-01-30 | — | — | EP | disclosed |
| US-9896550-B2 | Epoxy-modified silicone resin, making method, curable composition, and electronic part | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-02-20 | — | — | US | disclosed |
| US-9896550-B2 | Epoxy-modified silicone resin, making method, curable composition, and electronic part | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-02-20 | — | — | US | disclosed |
| US-9840484-B2 | Aryl compound and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-12-12 | — | — | US | disclosed |
| US-9840484-B2 | Aryl compound and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-12-12 | — | — | US | disclosed |
| US-20170197928-A1 | ARYL COMPOUND AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-07-13 | — | — | US | disclosed |
| US-20170198102-A1 | EPOXY-MODIFIED SILICONE RESIN, MAKING METHOD, CURABLE COMPOSITION, AND ELECTRONIC PART | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-07-13 | — | — | US | disclosed |
| US-20170197928-A1 | ARYL COMPOUND AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-07-13 | — | — | US | disclosed |
| US-20170198102-A1 | EPOXY-MODIFIED SILICONE RESIN, MAKING METHOD, CURABLE COMPOSITION, AND ELECTRONIC PART | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-07-13 | — | — | US | disclosed |
| EP-3190144-A1 | EPOXY-MODIFIED SILICONE RESIN, MAKING METHOD, CURABLE COMPOSITION, AND ELECTRONIC PART | Shin-Etsu Chemical Co., Ltd. (JP) | 2017-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197928-A1 | ARYL COMPOUND AND MAKING METHOD | AHR, TET2, NAT1 | GABRA1 1366/4885GABRB2 1873/4885HSD17B1 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.