Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1257364 | 0.91 | GABRA1 (0.52) | CYP1A2BACE1ALOX5HSD17B1ESR2 | |
| SCHEMBL19104720 | 0.87 | GABRA1 (0.48) | CYP1A2BACE1ALOX5HSD17B1ESR2 | |
| SCHEMBL20684744 | 0.83 | APP (0.41) | CYP1A2BACE1ALOX5HSD17B1ESR2 | |
| SCHEMBL12247921 | 0.83 | HSD17B1 (0.46) | CYP1A2HSD17B1ESR2GABRA1GABRB2 | |
| SCHEMBL1023129 | 0.78 | HSD17B1 (0.66) | CYP1A2BACE1ALOX5HSD17B1KDM4E | |
| SCHEMBL50409 | 0.77 | BACE1 (0.62) | CYP1A2BACE1ALOX5HSD17B1KDM4E | |
| SCHEMBL9716759 | 0.76 | BACE1 (0.61) | CYP1A2BACE1ALOX5HSD17B1KDM4E | |
| SCHEMBL9446145 | 0.76 | EGFR (0.44) | CYP1A2ALDH1A1LMNAHPGDALOX15 | |
| SCHEMBL27694509 | 0.76 | CYP1A2 (0.51) | CYP1A2BACE1ALOX5HSD17B1KDM4E | |
| SCHEMBL251843 | 0.75 | AKR1B1 (0.56) | KDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351964-B1 | SILANYL PHENOLS AND NAPHTHOLS | CIBA SC HOLDING AG (CH) | 2007-04-11 | — | — | EP | disclosed |
| US-7078550-B2 | Silanyl phenols and naphthols | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-07-18 | — | — | US | disclosed |
| US-20040058891-A1 | Silanyl phenols and naphthols | CIBA SPECIALTY CHEMICALS CORP. | 2004-03-25 | — | — | US | disclosed |
| EP-1351964-A2 | SILANYL PHENOLS AND NAPHTHOLS | Ciba SC Holding AG (CH) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002058016-A2 | SILANYL PHENOLS AND NAPHTHOLS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058891-A1 | Silanyl phenols and naphthols | FOS, OSBP, CBR1 | CYP1A2 1065/4885BACE1 4415/4885ALOX5 1491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.