SCHEMBL239755

SCHEMBL239755

C=C(C)Cc1cc(Cc2ccc(O)c(CC(=C)C)c2)ccc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 1/20 0.48
▸ ESR2 Q92731 1/20 0.48
▸ CA1 P00915 1/20 0.48
▸ CA2 P00918 1/20 0.48
▸ CA4 P22748 1/20 0.48
▸ CA6 P23280 1/20 0.48
▸ GABRA1 P14867 1/20 0.43
▸ GABRB2 P47870 1/20 0.43
▸ MAPT P10636 2/20 0.41
▸ IDH1 O75874 1/20 0.41
▸ BACE1 P56817 1/20 0.41
▸ KLKB1 P03952 1/20 0.40
▸ CTSB P07858 1/20 0.40
▸ MMP9 P14780 1/20 0.40
▸ DNMT1 P26358 1/20 0.40
▸ DNMT3B Q9UBC3 1/20 0.40
▸ DNMT3L Q9UJW3 1/20 0.40
▸ DNMT3A Q9Y6K1 1/20 0.40
▸ GAA P10253 2/20 0.39
▸ KMT2A Q03164 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5882791 0.87 TRPA1 (0.53) ESR1ESR2GABRA1GABRB2MAPT
SCHEMBL28390526 0.84 CNR1 (0.55) GABRA1GABRB2BACE1KDM4ERAB9A
SCHEMBL9446145 0.80 EGFR (0.44) ALOX15
SCHEMBL1257364 0.80 GABRA1 (0.52) ESR1ESR2GABRA1GABRB2MAPT
SCHEMBL30523630 0.79 ALDH1A1 (0.59) MAPTGAAKDM4ERAB9APKM
SCHEMBL7046438 0.79 ALDH1A1 (0.59) MAPTGAAKDM4ERAB9APKM
SCHEMBL12035986 0.78 AMY1A (0.53) MAPTGAAKMT2AMEN1PKM
SCHEMBL31028402 0.78 AMY1A (0.53) MAPTGAAKMT2AMEN1PKM
SCHEMBL14230974 0.77 TSHR (0.45) CA1CA2MAPTKMT2AKDM4E
SCHEMBL19104720 0.77 GABRA1 (0.48) ESR1ESR2GABRA1GABRB2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4100140-A REACTING POLYMALEIMIDES WITH ALKENYLPHENOLS OR ALKENYLPHENOL ETHERS, POLYMERIZATION CATALYSTS CIBA-GEIGY CORPORATION (US) 1978-07-11 — — US claimed
US-9512333-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2016-12-06 — — US disclosed
EP-2417168-B1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS HUNTSMAN ADV MAT AMERICAS INC (US) 2014-11-26 — — EP disclosed
EP-2710045-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS Huntsman Advanced Materials Americas LLC (US) 2014-03-26 — — EP disclosed
US-20140057086-A1 Halogen Free Thermoset Resin System for Low Dielectric Loss at High Frequency Applications HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2014-02-27 — — US disclosed
US-20130231021-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-09-05 — — US disclosed
US-8445699-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-05-21 — — US disclosed
WO-2012158415-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2012-11-22 — — WO disclosed
US-20120003892-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions Huntsman Advanced Materials Americans LLC (US) 2012-01-05 — — US disclosed
US-8043534-B2 An adhesive comprising a maleimide and an aromatic diene or an aromatic monoene which cure to form useful thermosetting resins for the microelectronic packaging industry; semiconcuctor dies; addition polymerization/Diels-Alder reaction; heat and acid resistance; toughness; noncracking; nondestructive DESIGNER MOLECULES, INC. (US) 2011-10-25 — — US disclosed
US-5138000-A High strength molding material CIBA-GEIGY CORPORATION (US) 1992-08-11 — — US disclosed
EP-0458240-A1 Curable compositions CIBA-GEIGY AG (CH) 1991-11-27 — — EP disclosed
EP-0457732-A1 Curable compositions CIBA-GEIGY AG (CH) 1991-11-21 — — EP disclosed
EP-0348345-A2 Solution stable polyimide resin systems CIBA-GEIGY AG (CH) 1989-12-27 — — EP disclosed
EP-0227598-B1 STABLE COMPOSITIONS CONTAINING IMIDES CIBA-GEIGY AG (CH) 1989-08-02 — — EP disclosed
US-4749767-A IMPREGNATED YARN LAMINATE CIBA-GEIGY CORPORATION (US) 1988-06-07 — — US disclosed
EP-0235084-A2 Hot-curable compositions containing substituted bicyclo[2,2,1]hept-5-ene-2,3 imides of dicarboxylic acids and polymalein imide CIBA-GEIGY AG (CH) 1987-09-02 — — EP disclosed
US-4689378-A Stable imide-containing composition from diamino phenyl indane-bis-maleimide and alkenyl phenol CIBA-GEIGY CORPORATION (US) 1987-08-25 — — US disclosed
US-4678849-A PREPREGS, COMPOSITES, COATINGS CIBA-GEIGY CORPORATION (US) 1987-07-07 — — US disclosed
EP-0227598-A1 Stable compositions containing imides CIBA-GEIGY AG (CH) 1987-07-01 — — EP disclosed
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