Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 10/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 10/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.47 |
| ▸ | NQO2 | P16083 | 5/20 | 0.47 |
| ▸ | TTR | P02766 | 4/20 | 0.47 |
| ▸ | ABL1 | P00519 | 3/20 | 0.47 |
| ▸ | BCR | P11274 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12729845 | 1.00 | CYP1A1 (0.56) | CYP1A1CYP1B1CYP1A2NQO2TTR | |
| SCHEMBL5447309 | 0.87 | CYP1A1 (0.73) | CYP1A1CYP1B1CYP1A2NQO2TTR | |
| SCHEMBL16362233 | 0.85 | CYP1A1 (0.77) | CYP1A1CYP1B1CYP1A2NQO2TTR | |
| SCHEMBL13369584 | 0.82 | CYP1A1 (0.58) | CYP1A1CYP1B1CYP1A2NQO2TTR | |
| SCHEMBL12729847 | 0.80 | CYP1A1 (0.65) | CYP1A1CYP1B1CYP1A2NQO2TTR | |
| SCHEMBL10312395 | 0.78 | RELA (0.68) | CYP1A1CYP1B1CYP1A2NQO2TTR | |
| SCHEMBL12535856 | 0.78 | PTGS2 (0.78) | CYP1A1CYP1B1CYP1A2NQO2TTR | |
| SCHEMBL19187093 | 0.78 | THRB (0.59) | CYP1A1CYP1B1CYP1A2PTGS2KDM4E | |
| SCHEMBL11999776 | 0.78 | F3 (0.56) | CYP1A1CYP1B1CYP1A2NQO2TTR | |
| SCHEMBL12729855 | 0.77 | KDM4E (0.69) | CYP1A1CYP1B1CYP1A2NQO2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342047-A1 | Cancerous Cell Growth Inhibiting Compounds | WISYS TECHNOLOGY FOUNDATION, INC. | 2017-11-30 | — | — | US | disclosed |
| US-20170197897-A1 | Skin Lightening Compounds | WISYS TECH FOUND INC (US) | 2017-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342047-A1 | Cancerous Cell Growth Inhibiting Compounds | TYR, MKI67, MC1R | CYP1A1 226/4885CYP1B1 56/4885CYP1A2 329/4885 |
| US-20170197897-A1 | Skin Lightening Compounds | TYR, MC1R, MCHR1 | CYP1A1 75/4885CYP1B1 49/4885CYP1A2 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.