Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 2/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.66 |
| ▸ | NQO2 | P16083 | 4/20 | 0.66 |
| ▸ | ESR1 | P03372 | 4/20 | 0.66 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.66 |
| ▸ | TTR | P02766 | 3/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.66 |
| ▸ | TUBB | P07437 | 3/20 | 0.66 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.66 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.66 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.66 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.66 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.66 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.66 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.66 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.66 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12535856 | 0.92 | PTGS2 (0.78) | RELACYP1A1CYP1B1NQO2ESR1 | |
| SCHEMBL12667489 | 0.92 | CYP1A1 (0.77) | RELACYP1A1CYP1B1NQO2ESR1 | |
| SCHEMBL13984043 | 0.92 | CYP1A1 (0.77) | RELACYP1A1CYP1B1NQO2ESR1 | |
| SCHEMBL13409620 | 0.89 | RELA (0.81) | RELACYP1A1CYP1B1NQO2ESR1 | |
| SCHEMBL16362233 | 0.88 | CYP1A1 (0.77) | CYP1A1CYP1B1NQO2ESR1TUBB1 | |
| SCHEMBL14877842 | 0.87 | CYP1A1 (0.59) | RELACYP1A1CYP1B1NQO2ESR1 | |
| SCHEMBL12535853 | 0.87 | PTGS2 (0.80) | RELACYP1A1CYP1B1NQO2ESR1 | |
| SCHEMBL12729855 | 0.87 | KDM4E (0.69) | RELACYP1A1CYP1B1NQO2ESR1 | |
| SCHEMBL12729821 | 0.85 | PTGS2 (0.80) | RELACYP1A1CYP1B1NQO2ESR1 | |
| SCHEMBL16167739 | 0.84 | CYP1A1 (0.61) | CYP1A1CYP1B1NQO2ESR1TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178704-A1 | PREVENTION AND TREATMENT OF COLON CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178704-A1 | PREVENTION AND TREATMENT OF COLON CANCER | APC, SI, NFKBIA | RELA 20/4885CYP1A1 1123/4885CYP1B1 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.