Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.78 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.78 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.78 |
| ▸ | NQO2 | P16083 | 4/20 | 0.78 |
| ▸ | ESR1 | P03372 | 3/20 | 0.78 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.78 |
| ▸ | AHR | P35869 | 3/20 | 0.78 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.78 |
| ▸ | ABL1 | P00519 | 2/20 | 0.78 |
| ▸ | TTR | P02766 | 2/20 | 0.78 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.78 |
| ▸ | BCR | P11274 | 2/20 | 0.78 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.78 |
| ▸ | TUBB | P07437 | 1/20 | 0.78 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.78 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.78 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.78 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10312395 | 0.92 | RELA (0.68) | PTGS2CYP1A1CYP1B1NQO2ESR1 | |
| SCHEMBL12231884 | 0.92 | RELA (0.73) | PTGS2CYP1A1CYP1B1NQO2ESR1 | |
| SCHEMBL13409620 | 0.89 | RELA (0.81) | PTGS2CYP1A1CYP1B1NQO2ESR1 | |
| Trismethoxyresveratrol SCHEMBL918740 | 0.88 | CYP1A1 (1.00) | PTGS2CYP1A1CYP1B1NQO2ESR1 | |
| 8Z-3,4',5-Trimethoxystilbene SCHEMBL1006207 | 0.88 | CYP1A1 (1.00) | PTGS2CYP1A1CYP1B1NQO2ESR1 | |
| SCHEMBL16362233 | 0.88 | CYP1A1 (0.77) | PTGS2CYP1A1CYP1B1NQO2ESR1 | |
| SCHEMBL13443549 | 0.88 | CYP1A1 (0.91) | PTGS2CYP1A1CYP1B1NQO2ESR1 | |
| Trismethoxyresveratrol SCHEMBL918739 | 0.88 | CYP1A1 (1.00) | PTGS2CYP1A1CYP1B1NQO2ESR1 | |
| SCHEMBL3758141 | 0.88 | CYP1A1 (0.91) | PTGS2CYP1A1CYP1B1NQO2ESR1 | |
| SCHEMBL12535853 | 0.87 | PTGS2 (0.80) | PTGS2CYP1A1CYP1B1NQO2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234900-A1 | METHODS OF ARENE ALKENYLATION | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2023-07-27 | — | — | US | disclosed |
| US-20220213126-A1 | SMALL MOLECULE AUTOPHAGY INDUCERS FOR THE TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES | JOHN WAYNE CANCER INSTITUTE (US) | 2022-07-07 | — | — | US | disclosed |
| US-8716355-B2 | Hydroxylated tolans and related compounds in the treatment of a cancer | KENT STATE UNIVERSITY (US) | 2014-05-06 | — | — | US | disclosed |
| US-20110130468-A1 | HYDROXYLATED TOLANS AND RELATED COMPOUNDS IN THE TREATMENT OF A CANCER | KENT STATE UNIVERSITY (US) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234900-A1 | METHODS OF ARENE ALKENYLATION | CYBB, CBR3, AHR | PTGS2 1773/4885CYP1A1 90/4885CYP1B1 62/4885 |
| US-20220213126-A1 | SMALL MOLECULE AUTOPHAGY INDUCERS FOR THE TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES | TFEB, SQSTM1, BECN1 | PTGS2 2350/4885CYP1A1 4569/4885CYP1B1 4335/4885 |
| US-20110130468-A1 | HYDROXYLATED TOLANS AND RELATED COMPOUNDS IN THE TREATMENT OF A CANCER | TKT, HAAO, TTPA | PTGS2 2030/4885CYP1A1 387/4885CYP1B1 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.