Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4569282 | 0.81 | NCF1 (0.46) | JAK2JAK1TYK2NCF1 | |
| SCHEMBL14176504 | 0.79 | SAT1 (0.39) | JAK2JAK1TYK2 | |
| SCHEMBL8259142 | 0.79 | — | — | |
| SCHEMBL12444046 | 0.79 | JAK2 (0.31) | JAK2JAK1TYK2 | |
| SCHEMBL14768800 | 0.78 | OPRM1 (0.31) | JAK2JAK1TYK2 | |
| SCHEMBL10245112 | 0.78 | EPHX1 (0.41) | — | |
| SCHEMBL21214167 | 0.77 | GNAI3 (0.51) | NCF1 | |
| SCHEMBL16017510 | 0.76 | HRH3 (0.39) | — | |
| SCHEMBL16745494 | 0.76 | ACHE (0.41) | — | |
| SCHEMBL15371153 | 0.76 | TPSAB1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189839-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Taro Pharmaceuticals Inc. (CA) | 2017-07-12 | — | — | EP | disclosed |