Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7224472 | 0.98 | CHRM1 (0.53) | CHRM1CHRM3ADRA1ACHRM2CHRNA4 | |
| SCHEMBL20170459 | 0.98 | CHRM1 (0.53) | CHRM1CHRM3ADRA1ACHRM2CHRNA4 | |
| SCHEMBL20170447 | 0.98 | CHRM1 (0.53) | CHRM1CHRM3ADRA1ACHRM2CHRNA4 | |
| SCHEMBL7217444 | 0.91 | CHRM1 (0.59) | CHRM1CHRM3ADRA1ACHRM2CHRNA4 | |
| SCHEMBL14875486 | 0.89 | EPHX1 (0.48) | CHRM1CHRM3ADRA1ACHRM2CHRNA4 | |
| SCHEMBL3908224 | 0.88 | CA2 (0.54) | CHRM1CHRM3ADRA1ACHRM2CHRNA4 | |
| SCHEMBL22086821 | 0.88 | EPHX1 (0.42) | CHRM1CHRM3ADRA1ACHRM2CHRNA4 | |
| SCHEMBL5827222 | 0.87 | EPHX1 (0.52) | CHRM1CHRM3ADRA1ACHRM2CHRNA4 | |
| SCHEMBL27864138 | 0.87 | NAAA (0.55) | CHRM1CHRM3ADRA1ACHRM2CHRNA4 | |
| Ammonia Solution, Strong SCHEMBL11651733 | 0.87 | CA2 (0.53) | CHRM1CHRM3ADRA1ACHRM2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170196848-A1 | Prodrugs of NH-Acidic Compounds: Ester, Carbonate, Carbamate and Phosphonate Derivatives | ALKERMES PHARMA IRELAND LTD (IE) | 2017-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196848-A1 | Prodrugs of NH-Acidic Compounds: Ester, Carbonate, Carbamate and Phosphonate Derivatives | PHPT1, SI, CA6 | CHRM1 2813/4885CHRM3 3013/4885ADRA1A 4523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.