SCHEMBL19117

SCHEMBL19117

COC(=O)c1ccc([N+](=O)[O-])cc1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.60
CA12 O43570 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA7 P43166 1/20 0.59
PDK2 Q15119 1/20 0.59
PDK4 Q16654 1/20 0.59
CA9 Q16790 1/20 0.59
CA14 Q9ULX7 1/20 0.59
KMT2A Q03164 3/20 0.55
ALDH1A1 P00352 3/20 0.55
GPR35 Q9HC97 2/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
MEN1 O00255 2/20 0.50
HTT P42858 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
NPC1 O15118 1/20 0.50
HSP90AA1 P07900 1/20 0.50
MAPT P10636 1/20 0.50
PKM P14618 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29448257 0.87 L3MBTL1 (0.62) GAACA12CA1CA2CA7
SCHEMBL391334 0.87 L3MBTL1 (0.62) GAACA12CA1CA2CA7
SCHEMBL1403472 0.86 ALDH1A1 (0.56) GAAKMT2AALDH1A1SMN1; SMN2MEN1
SCHEMBL30203403 0.86 ALDH1A1 (0.56) GAAKMT2AALDH1A1SMN1; SMN2MEN1
Methane SCHEMBL27588822 0.85 ALDH1A1 (0.54) GAAKMT2AALDH1A1SMN1; SMN2MEN1
SCHEMBL6960199 0.83 KDM4E (0.55) KMT2AALDH1A1GPR35SMN1; SMN2MEN1
SCHEMBL3835248 0.83 MEN1 (0.51) GAACA12CA1CA2CA7
SCHEMBL1163261 0.83 ADRB2 (0.56) GAAKMT2AALDH1A1SMN1; SMN2MEN1
SCHEMBL5925545 0.83 SMN1; SMN2 (0.65) CA12CA1CA2CA7CA9
SCHEMBL16423530 0.83 ALDH1A1 (0.51) GAAKMT2AALDH1A1GPR35SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101348444-B Preparation of 2-ethoxy-4-acetaminobenzoic acid methyl ester ZHEJIANG ESIGMA ANIMAL HEALTH CO LTD 2012-01-11 CN claimed
CN-101348444-A Preparation of 2-ethoxy-4-acetaminobenzoic acid methyl ester ZHEJIANG HUINENG ANIMALS LEECH (CN) 2009-01-21 CN claimed
US-20060110743-A1 Drug evolution: drug design at hot spots KONISHI YASUO 2006-05-25 US claimed
WO-2002095393-A2 DRUG EVOLUTION: DRUG DESIGN AT HOT SPOTS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2002-11-28 WO claimed
CN-122094675-A Deuterated organic compounds and use thereof 2026-05-26 CN disclosed
EP-4734983-A2 DEUTERATED ORGANIC COMPOUNDS AND USES THEREOF Engrail Therapeutics, Inc. (US) 2026-05-06 EP disclosed
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-11-20 US disclosed
EP-4547671-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 EP disclosed
CN-119859155-A Tri-fused ring derivative inhibitor, preparation method and application thereof 江苏豪森药业集团有限公司 2025-04-22 CN disclosed
WO-2025010255-A2 DEUTERATED ORGANIC COMPOUNDS AND USES THEREOF ENGRAIL THERAPEUTICS, INC. (US) 2025-01-09 WO disclosed
CN-119255997-A Modulators of c-MYC mRNA translation and their use in the treatment of cancer 艾尼莫生物科技公司 2025-01-03 CN disclosed
WO-2024010761-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 WO disclosed
WO-2000064864-A9 N-PROTECTED AMINES AND THEIR USE AS PRODRUGS CANCER RES CAMPAIGN TECH (GB) 2001-12-27 WO disclosed
WO-2000064864-A1 N-PROTECTED AMINES AND THEIR USE AS PRODRUGS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 2000-11-02 WO disclosed
EP-0133423-B1 USE OF 4,5'-AZO-BIS-SALICYLIC ACID FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF INFLAMMATORY DISORDERS IN THE INTESTINE PHARMACIA AB (SE) 1987-11-25 EP disclosed
US-4591584-A ANTIINFLAMMATORY AGENTS; GASTRO INTESTINAL DISORDERS PHARMACIA AB (SE) 1986-05-27 US disclosed
EP-0145777-A1 AZO-BIS-SALICYLIC ACID AND SALT THEREOF, PHARMACEUTICAL FORMULATIONS AND USES OF SAID ACID AND SALT, AND PRODUCTION OF THE ACID PHARMACIA AB (SE) 1985-06-26 EP disclosed
EP-0133423-A1 Use of 4,5'-azo-bis-salicylic acid for the manufacture of a medicament for the treatment of inflammatory disorders in the intestine PHARMACIA AB (SE) 1985-02-20 EP disclosed
WO-1985000013-A1 AZO-BIS-SALICYLIC ACID AND SALT THEREOF, PHARMACEUTICAL FORMULATIONS AND USES OF SAID ACID AND SALT, AND PRODUCTION OF THE ACID PHARMACIA AB (SE) 1985-01-03 WO disclosed
US-4006239-A Benzoic acid amides for mycobacterium infections BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 GAA 3895/4885CA12 4693/4885CA1 4879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.