Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352384 | 0.87 | ALDH1A1 (0.37) | KMT2AALDH1A1MEN1KDM4ENPSR1 | |
| SCHEMBL19119229 | 0.83 | ROCK2 (0.42) | KMT2AALDH1A1MEN1RAB9ACYP2C19 | |
| SCHEMBL19119451 | 0.83 | THRB (0.36) | LMNAMAPT | |
| SCHEMBL19119282 | 0.82 | RAB9A (0.33) | KMT2AALDH1A1NPSR1HTTRAB9A | |
| SCHEMBL19118760 | 0.81 | NPSR1 (0.34) | KMT2AALDH1A1NPSR1HTTRAB9A | |
| SCHEMBL19119501 | 0.78 | HTT (0.35) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL19119290 | 0.78 | KMT2A (0.32) | KMT2AALDH1A1LMNAHTTRAB9A | |
| SCHEMBL19118721 | 0.77 | S1PR2 (0.36) | KMT2AMEN1LMNAMAPTRAB9A | |
| SCHEMBL19119383 | 0.77 | THRB (0.36) | ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL19119086 | 0.77 | SHMT2 (0.31) | KMT2AALDH1A1KDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200440-B1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | CRESTONE INC (US) | 2017-07-19 | — | — | EP | claimed |