Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | CFD | P00746 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 4/20 | 0.44 |
| ▸ | NOS2 | P35228 | 4/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370932 | 0.85 | CFD (0.53) | LOXL2CFDHTR6CA12CA1 | |
| SCHEMBL27480162 | 0.82 | AKR1C3 (0.43) | CA12CA1CA2CA9CA4 | |
| SCHEMBL28250673 | 0.80 | POLB (0.47) | LOXL2CFDHTR6CA12CA1 | |
| SCHEMBL28141068 | 0.80 | MTNR1A (0.61) | LOXL2CFDHTR6NOS1NOS2 | |
| SCHEMBL2545099 | 0.79 | ALDH1A1 (0.61) | LOXL2CFDALDH1A1SMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL1127877 | 0.78 | ALDH1A1 (0.59) | LOXL2CFDALDH1A1CYP1A2TSHR | |
| SCHEMBL2642459 | 0.77 | HTR6 (0.47) | LOXL2CFDHTR6NOS1NOS2 | |
| SCHEMBL28032753 | 0.77 | CYP3A4 (0.55) | LOXL2CFDHTR6NOS1NOS2 | |
| Acetic Acid SCHEMBL14931327 | 0.76 | HTR6 (0.46) | LOXL2CFDHTR6NOS1NOS2 | |
| SCHEMBL371031 | 0.76 | HDAC4 (0.40) | NOS1NOS2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200440-B1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | CRESTONE INC (US) | 2017-07-19 | — | — | EP | disclosed |