Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27165476 | 0.84 | ALDH1A1 (0.38) | POLBALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL17318077 | 0.80 | GAA (0.31) | ALDH1A1KDM4EMEN1USP2LMNA | |
| SCHEMBL17848825 | 0.78 | MEN1 (0.33) | ALDH1A1KDM4EMEN1USP2LMNA | |
| SCHEMBL13655626 | 0.77 | ATM (0.45) | L3MBTL1ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL18803167 | 0.76 | GAA (0.42) | POLBL3MBTL1KMT2ATDP1JAK2 | |
| SCHEMBL28395559 | 0.75 | ATM (0.43) | L3MBTL1ALDH1A1MEN1LMNAHPGD | |
| SCHEMBL13655637 | 0.73 | L3MBTL1 (0.48) | POLBL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL29969222 | 0.73 | CA2 (0.39) | POLBKMT2AJAK2JAK1GAA | |
| SCHEMBL17848849 | 0.72 | JAK2 (0.33) | JAK2JAK1 | |
| SCHEMBL15832603 | 0.70 | ALDH1A1 (0.53) | ALDH1A1KDM4EMEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218376-A1 | APTAMER-TYPE MULTI-WARHEAD COVALENT DRUG | YANG, JAY (JP) | 2024-07-04 | — | — | US | disclosed |
| US-20240218376-A1 | APTAMER-TYPE MULTI-WARHEAD COVALENT DRUG | YANG, JAY (JP) | 2024-07-04 | — | — | US | disclosed |
| US-20170196985-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2017-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196985-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | CYP2F1, NAF1, CYP2S1 | POLB 2700/4885NPSR1 341/4885L3MBTL1 4222/4885 |
| US-20240218376-A1 | APTAMER-TYPE MULTI-WARHEAD COVALENT DRUG | ACE2, WRN, SARS1 | POLB 395/4885NPSR1 4202/4885L3MBTL1 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.