Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26709266 | 0.86 | CASP2 (0.59) | EPHX2CASP2FAAH | |
| SCHEMBL19686832 | 0.86 | CASP2 (0.59) | EPHX2CASP2FAAH | |
| SCHEMBL19123705 | 0.86 | ACHE (0.70) | ACHEEPHX2 | |
| SCHEMBL19123782 | 0.86 | ACHE (0.70) | ACHEEPHX2 | |
| SCHEMBL16301543 | 0.85 | ACHE (0.60) | ACHEEPHX2CASP2FAAH | |
| SCHEMBL25110172 | 0.85 | FAAH (0.50) | EPHX2CASP2FAAHTLR2 | |
| SCHEMBL25110154 | 0.84 | TLR2 (0.49) | EPHX2FAAHTLR2 | |
| SCHEMBL23484962 | 0.83 | FAAH (0.56) | EPHX2CASP2FAAH | |
| SCHEMBL25108986 | 0.82 | TLR2 (0.47) | EPHX2CASP2FAAHTLR2 | |
| SCHEMBL21140253 | 0.82 | ACHE (0.42) | ACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190099493-A1 | Targeting Lipids | ARBUTUS BIOPHARMA CORPORATION (CA) | 2019-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190099493-A1 | Targeting Lipids | APOB, LY96, ABHD10 | ACHE 4582/4885EPHX2 1721/4885CASP2 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.