Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 2/20 | 0.37 |
| ▸ | HPD | P32754 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969097 | 0.85 | APLNR (0.40) | PYCR1NAAANPC1RAB9ABMP1 | |
| SCHEMBL12936612 | 0.81 | IDO1 (0.58) | PTPN1IDO1AGXT | |
| SCHEMBL12936610 | 0.80 | IDO1 (0.39) | PTPN1IDO1AGXT | |
| SCHEMBL29506818 | 0.79 | PYCR1 (0.46) | PYCR1NAAANPC1RAB9AIDO1 | |
| SCHEMBL582358 | 0.79 | PYCR1 (0.46) | PYCR1NAAANPC1RAB9AIDO1 | |
| SCHEMBL27686599 | 0.79 | NAAA (0.48) | PYCR1NAAANPC1RAB9AIDO1 | |
| SCHEMBL12936616 | 0.79 | IDO1 (0.38) | IDO1AGXTHPD | |
| SCHEMBL27358340 | 0.79 | IDO1 (0.38) | NAAAPTPN1IDO1AGXTMEN1 | |
| SCHEMBL2093599 | 0.76 | PYCR1 (0.44) | PYCR1NAAANPC1RAB9AIDO1 | |
| SCHEMBL12964490 | 0.76 | IDO1 (0.61) | IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170204086-A1 | ALPHA-HELIX ANALOG HAVING TRIAZINE-PIPERAZINE BACKBONE AND METHOD FOR PREPARING SAME | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2017-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204086-A1 | ALPHA-HELIX ANALOG HAVING TRIAZINE-PIPERAZINE BACKBONE AND METHOD FOR PREPARING SAME | HSPH1, HBZ, PITHD1 | PYCR1 2129/4885NAAA 3456/4885PTPN1 3448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.