Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | HPD | P32754 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800216 | 0.87 | APLNR (0.38) | APLNRBMP1RAB9AMAPTMEN1 | |
| SCHEMBL19129488 | 0.85 | PYCR1 (0.43) | APLNRNAAAPYCR1BMP1NPC1 | |
| SCHEMBL582358 | 0.79 | PYCR1 (0.46) | NAAAPYCR1NPC1RAB9AMTNR1B | |
| SCHEMBL29506818 | 0.79 | PYCR1 (0.46) | NAAAPYCR1NPC1RAB9AMTNR1B | |
| SCHEMBL27686599 | 0.75 | NAAA (0.48) | NAAAPYCR1NPC1RAB9AMEN1 | |
| SCHEMBL23148174 | 0.73 | PYCR1 (0.42) | NAAAPYCR1BMP1NPC1RAB9A | |
| SCHEMBL26205621 | 0.73 | FPR2 (0.40) | APLNRNAAABMP1MTNR1BMAPT | |
| SCHEMBL2093599 | 0.73 | PYCR1 (0.44) | NAAAPYCR1NPC1RAB9AMTNR1B | |
| SCHEMBL8421522 | 0.72 | PYCR1 (0.41) | NAAAPYCR1NPC1RAB9AMTNR1B | |
| SCHEMBL21203176 | 0.72 | PYCR1 (0.41) | APLNRNAAAPYCR1BMP1MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |