Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.32 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20857203 | 0.84 | TYMS (0.41) | — | |
| SCHEMBL19129852 | 0.82 | RNASE1 (0.36) | RNASE1TK1 | |
| SCHEMBL21560996 | 0.76 | TK1 (0.44) | TK1 | |
| SCHEMBL19130235 | 0.76 | RNASEL (0.49) | — | |
| SCHEMBL16158115 | 0.75 | TK1 (0.36) | RNASE1TK1P2RY1 | |
| SCHEMBL17635427 | 0.75 | TK1 (0.33) | TK1 | |
| SCHEMBL12865276 | 0.75 | TK1 (0.33) | TK1 | |
| SCHEMBL19152348 | 0.74 | TK1 (0.60) | RNASE1TK1 | |
| SCHEMBL12865604 | 0.67 | — | — | |
| SCHEMBL16154898 | 0.67 | TK1 (0.47) | RNASE1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170204152-A1 | CHIMERIC POLYNUCLEOTIDES | MODERNA THERAPEUTICS, INC. (US) | 2017-07-20 | — | — | US | disclosed |
| US-20170204422-A1 | CIRCULAR POLYNUCLEOTIDES | ARES CAPITAL CORPORATION, AS AGENT | 2017-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204152-A1 | CHIMERIC POLYNUCLEOTIDES | NSUN3, TRDMT1, NSUN2 | RNASE1 116/4885TK1 518/4885P2RY1 1904/4885 |
| US-20170204422-A1 | CIRCULAR POLYNUCLEOTIDES | POLN, POLRMT, POLI | RNASE1 56/4885TK1 452/4885P2RY1 1786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.